Chitosan Phonophresis on Cervical IN Smartphone Addicted Users

NCT06491992 | Recruiting

• 1 other identifier: O6U.PT.REC/024/002003
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers of N-acetylglucosamine and N-glucosamine. Its use has been explored in various biomaterial and medical applications. Chitosan has emerged as a cost-effective, biocompatible, and biodegradable material with many desirable biological properties, improvement of homeostasis and antiviral potential. Chitosan was found to suppress pro-inflammatory cytokines and decreased peripheral nerve edema, the polycationic nature of chitosan allows it to absorb protons, which reduces inflammation and provides an analgesic effect.

Conditions

Cervical Pain

Outcome Measures

Primary Outcomes (3)

• Smartphone Addiction Scale-Short Version (SAS-SV)

  SAS-SV was psychometrically robust in measuring the severity of smartphone addiction

  four weeks

• The visual analogue scale

  was utilized to evaluate pre- and post-treatment neck pain

  four weeks

• Neck disability index

  assess how neck pain and other symptoms manifested during various functional activities. Ndi had been reported as a reliable (Cronbach's alpha: 0.89) and valid instrument to evaluate self-rated disability in patients with neck pain

  four weeks

Secondary Outcomes (1)

• Cervical ROM

  four weeks

Study Arms (2)

study group

EXPERIMENTAL

Chitosan Phonophresis intervention

Drug: Chitosan Phonophresis; Other: selected physical therapy exercise

control group

EXPERIMENTAL

the selected exercise program

Other: selected physical therapy exercise

Interventions

Chitosan Phonophresis DRUG

Chitosan Phonophresis, three times per week for four weeks.

study group

selected physical therapy exercise OTHER

selected neck exercise and electrotherapy on cervical region

control group; study group

Eligibility Criteria

• Age: 16 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Their age will be ranged from 16-18 years
• body mass index will be 26.58 kg/m2.
• used a smart phone for more than 1 year for at least 2 hours per day
• complaining of neck pain after using a smart phone, addiction to smart phone in accordance with the smart phone addiction scale (SAS)

You may not qualify if:

• any previous head and neck injuries or surgeries
• any congenital abnormalities or symptomatic deformity in either the cervical or the lumbar spine
• any uncorrected visual or auditory problems, dizziness, vertigo and headache
• any systematic diseases, any addiction to alcohol, any additive drugs and sedatives within 48 hours previous to tests
• body mass index of subjects over25 kg/m2.

Sponsors & Collaborators

• October 6 University: lead

Study Sites (1)

Lama S Mahmoud

Al Jīzah, Select State, Egypt

RECRUITING

MeSH Terms

Conditions

Neck Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Lama Saad El-Din ED Mahmoud

CONTACT

01157592636; lamaelsedawyy@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lama Saad El-Din Mahmoud

Study Record Dates

• First Submitted: July 1, 2024
• First Posted: July 9, 2024
• Study Start: July 1, 2024
• Primary Completion: September 30, 2024
• Study Completion: October 15, 2024
• Last Updated: July 9, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)