NCT06487741

Brief Summary

This randomised controlled trial will examine the clinical efficacy of a six-week, novel, home-based stretching programme compared to usual care on the effect of symptoms experienced by patients with fibromyalgia.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
58

participants targeted

Target at P25-P50 for not_applicable

Timeline
4mo left

Started Oct 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress83%
Oct 2024Aug 2026

First Submitted

Initial submission to the registry

June 27, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 5, 2024

Completed
4 months until next milestone

Study Start

First participant enrolled

October 31, 2024

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2026

Last Updated

February 17, 2025

Status Verified

November 1, 2024

Enrollment Period

1.8 years

First QC Date

June 27, 2024

Last Update Submit

February 12, 2025

Conditions

Keywords

FibromyalgiaStretching exercisesHome-basedAdherence

Outcome Measures

Primary Outcomes (3)

  • Severity of symptoms

    The Revised Fibromyalgia Impact Questionnaire (FIQ-R) total score

    Measured at baseline

  • Severity of symptoms

    The Revised Fibromyalgia Impact Questionnaire (FIQ-R) total score

    Measured following 6 weeks of intervention (primary endpoint)

  • Severity of symptoms

    The Revised Fibromyalgia Impact Questionnaire (FIQ-R) total score

    Measured 6 months after the primary endpoint (secondary endpoint)

Secondary Outcomes (10)

  • Health-Related Quality of life (HRQL)

    Measured at baseline

  • Health-Related Quality of life (HRQL)

    Measured following 6 weeks of intervention (primary endpoint)

  • Health-Related Quality of life (HRQL)

    Measured 6 months after the primary endpoint (secondary endpoint)

  • Self-reported physical activity

    Measured at baseline

  • Self-reported physical activity

    Measured following 6 weeks of intervention (primary endpoint)

  • +5 more secondary outcomes

Other Outcomes (1)

  • Adherence

    Measured following 6 weeks of intervention (primary endpoint)

Study Arms (2)

Intervention

EXPERIMENTAL

The intervention group receives a home-based rehabilitation program consisting of six weeks of daily static stretching exercises (six minutes a day).

Other: Home-based stretching exercises

Control

NO INTERVENTION

The control group receives usual care, and no change in treatment is made. Participants will be encouraged to maintain their daily routine but refrain from changing the current pharmacological treatment or initiating new physical exercise practices during the study.

Interventions

The intervention comprises six weeks of daily static stretching exercises (six minutes a day) in accordance with the recommendation of the American College of Sports Medicine. The intervention is self-administered and consists of two bouts of 30-second bilateral static stretches of the knee flexors, hip abductors, and shoulder elevators.

Intervention

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • individuals diagnosed with fibromyalgia in accordance with the ACR 2016 diagnostic criteria.
  • individuals diagnosed with chronic non-malignant pain or individuals diagnosed with chronic widespread pain (including fibromyalgia syndrome) are also included when they meet the ACR 2016 diagnostic criteria.

You may not qualify if:

  • Non-controlled systemic disorders (such as hypertension, diabetes and coronary insufficiency),
  • neurological conditions that impair alertness or comprehension, musculoskeletal conditions that could compromise assessments (such as nerve root compression or knee joint inflammation),
  • relevant joint disorders (such as severe arthritis, arthroplasty of the hip or knee, and rheumatoid arthritis),
  • recent changes in therapy for fibromyalgia (i.e., within four weeks of baseline).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University College of Northern Denmark

Aalborg, 9220, Denmark

RECRUITING

Related Publications (1)

  • Stove MP, Magnusson SP, Thomsen JL, Riis A. Efficacy of a home-based stretching programme on fibromyalgia symptoms: study protocol for a randomised controlled trial. Trials. 2025 Feb 27;26(1):74. doi: 10.1186/s13063-025-08776-z.

MeSH Terms

Conditions

FibromyalgiaTreatment Adherence and Compliance

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeuromuscular DiseasesNervous System DiseasesHealth BehaviorBehavior

Study Officials

  • Lise Eckardt, Pt. Msc

    Department of Physiotherapy, University College of Northern Denmark

    STUDY DIRECTOR

Central Study Contacts

Morten P Støve, PT. Msc.

CONTACT

Allan Riis, PT. Ph.D.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
Participants are blinded to the results of the pressure pain threshold measurements. Participants and the outcome assessor are blinded to the range of motion measurement results. The outcome assessor (MPS) is blinded to the outcome of the FIQ-R, SF-36 and IPAQ questionnaires. Blinding participants and the care provider (MPS) from delivering the intervention from treatment allocation is contrary to the nature of the investigated intervention and, therefore, is not considered feasible.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 27, 2024

First Posted

July 5, 2024

Study Start

October 31, 2024

Primary Completion (Estimated)

August 30, 2026

Study Completion (Estimated)

August 30, 2026

Last Updated

February 17, 2025

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will share

The study protocol will be published open access. Data is made available upon reasonable request.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
The study protocol will be published open access.
Access Criteria
Data is made available upon request.

Locations