Study of the Prevalence of Diabetes and Pre-diabetes in Réunion Island

NCT06473584 | Recruiting

• 1 other identifier: 2023/CHU/42
• Study Type: interventional
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

In view of the new priority given to diabetes in Réunion and the implementation of an ambitious plan to combat the disease at regional level, which includes the identification and management of pre-diabetes, the need for up-to-date data on the extent of these 2 diseases (diabetes and pre-diabetes) has become essential. These two diseases have known risk factors: age, overweight, obesity, high waist circumference, family history, hypertension, eating habits and physical activity, all of which form part of a risk score for developing diabetes: the Findrisk recommended by the Haute Autorité de Santé for identifying people at risk of diabetes. Given the specific population characteristics of Réunion compared with Finland, where this score has been validated, it would seem important to be able to measure these risk indicators in the population as a function of carbohydrate status in order to check that the proposed thresholds are appropriate for the population of Réunion. Finally, cardiovascular risk has been described as early as the pre-diabetes stage. Given the young age of onset of diabetes in Réunion and the high proportion of diagnoses of diabetes made following the occurrence of a cardiovascular complication, the study of the prognosis of carbohydrate status on the occurrence of complications using the social security information system will be offered on a voluntary basis to study subjects (via a probabilistic social security link).

Conditions

Diabetes

Outcome Measures

Primary Outcomes (1)

• Estimating the prevalence of glycaemic abnormalities (diabetes and pre-diabetes) in Réunion

  Measurement of fasting blood glucose and blood glucose 2 hours after ingesting 75g of glucose (HGPO test) according to Haute Autorite de Sante (HAS) recommendations used in France for diagnosing diabetes and pre-diabetes in people with unknown diabetes

  Day 1

Study Arms (1)

Detection of glycaemic anomalies

OTHER

Diagnostic Test: Diabetes detection

Interventions

Diabetes detection DIAGNOSTIC_TEST

Fasting glycemia on blood sample

Detection of glycaemic anomalies

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Have lived in Réunion island for at least one year
• Be aged between 18 and 75
• Affiliated to or benefiting from a social security scheme
• Free, informed and signed consent

You may not qualify if:

• No main residence on the island or fixed address for at least one year on the island
• Participation in experimental research
• Pregnant women
• Adults under guardianship or legal protection
• Not understanding French

Sponsors & Collaborators

• Centre Hospitalier Universitaire de la Réunion: lead
• Agence Régionale de Santé de La Réunion: collaborator

Study Sites (1)

CHU La Réunion

Saint-Denis, Reunion

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Catherine MARIMOUTOU, MD, PhD

  CHU La Réunion

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Catherine MARIMOUTOU, MD, PhD

CONTACT

+262 (0)262 90 50 50; catherine.marimoutou@chu-reunion.fr

Florence LEFEBVRE D'HELLENCOURT

CONTACT

+262 262 75 34 71; florence.lefebvre-dhellencourt@chu-reunion.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 19, 2024
• First Posted: June 25, 2024
• Study Start: April 2, 2025
• Primary Completion: March 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: July 30, 2025

Record last verified: 2025-07

Locations

RE (1)