Effects of Common Meals on Appetite and Satiety

NCT06472011 | Completed

• 1 other identifier: HS-2024-0114
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The objectives of this study are to assess the impacts of meals composed of lean steak and potatoes (with a small portion of broccoli) in comparison to other common entrée/starch food combinations on metabolic and appetite responses.

Conditions

Healthy

Outcome Measures

Primary Outcomes (1)

• appetite response

  Using 100 mm visual analog scales (score from 0 to 100 and higher score means more)

  baseline (B), 15 minutes from B, 30 minutes from B, 45 minutes from B, 60 minutes from B, 90 minutes from B, 120 minutes from B, 150 minutes from B, 180 minutes from B, 210 minutes from B, 240 minutes from B

Secondary Outcomes (1)

• blood glucose

  baseline (B), 15 minutes from B, 30 minutes from B, 45 minutes from B, 60 minutes from B, 90 minutes from B, 120 minutes from B, 150 minutes from B, 180 minutes from B, 210 minutes from B, 240 minutes from B

Study Arms (7)

Arm 1 (lean steak and potatoes)

EXPERIMENTAL

lean steak and potatoes will be provided to subjects and primary and secondary outcomes will be measured at timelines explained under primary and secondary outcome measures.

Other: lean steak and potatoes

Arm 2 (lentil and sweet potato chili )

EXPERIMENTAL

lentil and sweet potato chili will be provided to subjects and primary and secondary outcomes will be measured at timelines explained under primary and secondary outcome measures.

Other: lentil and sweet potato chili

Arm 3 (macaroni and cheese)

EXPERIMENTAL

macaroni and cheese will be provided to subjects and primary and secondary outcomes will be measured at timelines explained under primary and secondary outcome measures.

Other: macaroni and cheese

Arm 4 (fish tacos)

EXPERIMENTAL

fish tacos will be provided to subjects and primary and secondary outcomes will be measured at timelines explained under primary and secondary outcome measures.

Other: fish tacos

Arm 5 (chicken and pea fried rice)

EXPERIMENTAL

chicken and pea fried rice will be provided to subjects and primary and secondary outcomes will be measured at timelines explained under primary and secondary outcome measures.

Other: chicken and pea fried rice

Arm 6 (pita and hummus)

EXPERIMENTAL

pita and hummus will be provided to subjects and primary and secondary outcomes will be measured at timelines explained under primary and secondary outcome measures.

Other: pita and hummus

Arm 7 (creamy pork pasta)

EXPERIMENTAL

creamy pork pasta will be provided to subjects and primary and secondary outcomes will be measured at timelines explained under primary and secondary outcome measures.

Other: creamy pork pasta

Interventions

lean steak and potatoes OTHER

Participants will be fed \~400 kcal lean steak and potatoes on one occasion to test for changes in blood glucose and insulin levels as well as appetite over a 4-hour period of time.

Arm 1 (lean steak and potatoes)

lentil and sweet potato chili OTHER

Participants will be fed \~400 kcal lentil and sweet potato chili on one occasion to test for changes in blood glucose and insulin levels as well as appetite over a 4-hour period of time.

Arm 2 (lentil and sweet potato chili )

macaroni and cheese OTHER

Participants will be fed \~400 kcal macaroni and cheese on one occasion to test for changes in blood glucose and insulin levels as well as appetite over a 4-hour period of time.

Arm 3 (macaroni and cheese)

fish tacos OTHER

Participants will be fed \~400 kcal fish tacos on one occasion to test for changes in blood glucose and insulin levels as well as appetite over a 4-hour period of time.

Arm 4 (fish tacos)

chicken and pea fried rice OTHER

Participants will be fed \~400 kcal chicken and pea fried rice on one occasion to test for changes in blood glucose and insulin levels as well as appetite over a 4-hour period of time.

Arm 5 (chicken and pea fried rice)

pita and hummus OTHER

Participants will be fed \~400 kcal pita and hummus on one occasion to test for changes in blood glucose and insulin levels as well as appetite over a 4-hour period of time.

Arm 6 (pita and hummus)

creamy pork pasta OTHER

Participants will be fed \~400 kcal creamy pork pasta on one occasion to test for changes in blood glucose and insulin levels as well as appetite over a 4-hour period of time.

Arm 7 (creamy pork pasta)

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• ages of 18-50 years
• BMI between 18-26

You may not qualify if:

• special dietary needs (e.g., gluten-free, etc.),
• % weight change in the previous 2 months,
• smoking, and substance use.

Sponsors & Collaborators

• San Diego State University: lead

Study Sites (1)

San Diego State University

San Diego, California, 92182-7251, United States

Location

MeSH Terms

Interventions

Cheese

Intervention Hierarchy (Ancestors)

Cultured Milk Products; Milk; Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Fermented Foods; Dairy Products; Food; Food and Beverages

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: 7 crossover arms for each subject

Study Record Dates

• First Submitted: June 18, 2024
• First Posted: June 24, 2024
• Study Start: August 7, 2024
• Primary Completion: March 22, 2025
• Study Completion: March 22, 2025
• Last Updated: August 27, 2025

Record last verified: 2025-08

Locations

US (1)