NCT06468891

Brief Summary

This study will contribute to the existing body of knowledge on stress urinary incontinence and its impact on gait. The findings may have implications for the development of targeted interventions and rehabilitation strategies to improve mobility and quality of life in women with stress urinary incontinence

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
124

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 16, 2024

Completed
Same day until next milestone

Study Start

First participant enrolled

June 16, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 21, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 20, 2024

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 30, 2024

Completed
Last Updated

June 21, 2024

Status Verified

June 1, 2024

Enrollment Period

2 months

First QC Date

June 16, 2024

Last Update Submit

June 16, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Incontinence Symptom Severity Index

    The Incontinence Symptom Severity Index (ISSI) is a self-assessment instrument used to measure the severity of female urinary storage and voiding symptoms.

    one day

Secondary Outcomes (2)

  • Force platform

    one day

  • The STT three-dimensional motion analysis (3DMA) system

    one day

Study Arms (2)

women with stress urinary incontinence

This group includes 62 participants with chronic stress urinary incontinence.

Other: Incontinence Symptom Severity IndexOther: Force platformOther: The STT three-dimensional motion analysis (3DMA) system

women without stress urinary incontinence

This group includes 62 participants who are free from urinary incontinence symptoms and pelvic floor dysfunction.

Other: Incontinence Symptom Severity IndexOther: Force platformOther: The STT three-dimensional motion analysis (3DMA) system

Interventions

* The ISSI consists of eight items that assess different aspects of urinary incontinence symptoms, including emptying difficulties, nocturia, daytime frequency, stress incontinence, urge incontinence, leakage with activity, and pad use. * Each item is scored on a scale of (0 to 3) or (0 to 4), depending on the severity of the symptom. Higher scores indicate more severe symptoms. * The total ISSI score is obtained by summing the scores of all eight items, resulting in a range of 0 to 32 or 0 to 40, depending on the version used. * The severity of urinary incontinence symptoms can be categorized based on the total ISSI score

Also known as: (ISSI).
women with stress urinary incontinencewomen without stress urinary incontinence

Use the provided software or tools to analyze the recorded force data, including Step Cycle Duration (ms), Time of Contact (ms), Swing Duration (ms), Single Step Duration (ms), Double Support Duration (ms), Initial Contact (ms) , Loading Response (ms), Mid Stance (ms), Terminal Stance (ms), Step Cycle Length, Half Step Length for left and right lower limbs. * Interpret the data to draw conclusions about the forces exerted during the subject's movements or activities.

women with stress urinary incontinencewomen without stress urinary incontinence

The STT three-dimensional motion analysis (3DMA) system (STT Systems Company, Zuatzu Business Park, Easo Building, 2nd Floor, San Sebastián, Spain) was used for the assessment of spatiotemporal characteristics of gait. It is an indoor optical system that consists of four cameras, fifteen markers, and computer software for automatic three-dimensional motion capture and analysis. CLINICAL 3DMA V.6.11 is professional software with highly accurate marker tracking. The STT Helen Hayes protocol was used for the gait analysis in this study.

women with stress urinary incontinencewomen without stress urinary incontinence

Eligibility Criteria

Age40 Years - 60 Years
Sexfemale
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

One hundred twenty-four female participants who have stress urinary incontinence will participate in this study. Their ages will be ranged from 40 to 60 years. The participants will be selected from Mansoura University Hospitals and randomly distributed into two equal groups in numbers.

You may qualify if:

  • Age between 40-60 years old.
  • Women with BMI ≥30.
  • Women are free from any other gynecological disorders or symptoms that may affect the results of the study.
  • All participants who will be enrolled in the study sign the informed consent form.
  • All participants will be of multiparas.
  • All participants will be diagnosed with a mild degree of stress urinary incontinence.

You may not qualify if:

  • Pregnancy
  • Neurological Disorders: such as Parkinson's disease , multiple sclerosis, or any neurological dysfunction that may affect the gait parameters
  • Musculoskeletal disorders: such as severe osteoarthritis or lower limb amputations
  • Significant cognitive impairment: or dementia
  • Previous pelvic surgery as pelvic organ prolapse repair or anti-incontinence procedures.
  • Other significant medical conditions that could affect gait include severe cardiovascular disease or severe respiratory conditions.
  • Walking pain.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Physiotherapy

Cairo, 11432, Egypt

RECRUITING

Related Publications (1)

  • Elabd OM, Etoom M, Jahan AM, Elabd AM, Khedr AM, Elgohary HM. The Efficacy of Muscle Energy and Mulligan Mobilization Techniques for the Upper Extremities and Posture after Breast Cancer Surgery with Axillary Dissection: A Randomized Controlled Trial. J Clin Med. 2024 Feb 8;13(4):980. doi: 10.3390/jcm13040980.

Related Links

MeSH Terms

Conditions

Urinary Incontinence, Stress

Interventions

Drug Delivery Systems

Condition Hierarchy (Ancestors)

Urinary IncontinenceUrination DisordersUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Drug TherapyTherapeutics

Central Study Contacts

Fayiz F El Shamy, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Cairo University

Study Record Dates

First Submitted

June 16, 2024

First Posted

June 21, 2024

Study Start

June 16, 2024

Primary Completion

August 20, 2024

Study Completion

August 30, 2024

Last Updated

June 21, 2024

Record last verified: 2024-06

Data Sharing

IPD Sharing
Will not share

Locations