NCT06467214

Brief Summary

Social isolation is a negative social determinant of health that affects 1-in-5 adults in the U.S. and 43% of Veterans. Social isolation is estimated to cost the nation $6.7 billion annually in federal healthcare spending. Yet, social isolation has rarely been the direct focus of healthcare interventions. The proposed project is a randomized controlled trial that seeks to test the effectiveness of the Increasing Veterans' Social Engagement and Connectedness (CONNECTED) intervention on social isolation among diverse Veteran groups in primary care clinics. Increasing Veterans' Social Engagement and Connectedness involves three key services delivered by peers via telehealth through individual and group sessions over 8 weeks: 1) peer support, which includes person-centered assessment for social isolation, 2) psychosocial interventions to address social isolation, and 3) navigation (i.e., connecting Veterans to social resources). Findings from this study will contribute to the VA's efforts to address social determinants of health among Veterans and to provide high quality, person-centered, and equitable care to all Veterans.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
264

participants targeted

Target at P75+ for not_applicable

Timeline
25mo left

Started Oct 2024

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress45%
Oct 2024Jun 2028

First Submitted

Initial submission to the registry

June 14, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 20, 2024

Completed
4 months until next milestone

Study Start

First participant enrolled

October 4, 2024

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2028

Last Updated

July 18, 2025

Status Verified

July 1, 2025

Enrollment Period

3.7 years

First QC Date

June 14, 2024

Last Update Submit

July 17, 2025

Conditions

Keywords

VeteransPeer specialistsLonelinessNavigation

Outcome Measures

Primary Outcomes (1)

  • Lubben Social Network Scale-6

    The Lubben Social Network Scale-6 is a widely used, 6-item, self-reported measure of social isolation. It measures the frequency, size, and closeness of contact from respondents' social network. The scale has been used in both young and older adult populations, in racially diverse groups and in various settings and countries. Items are scored on a 6-point Likert scale, with total scores ranging from 0 (minimum) to 30 (maximum). Scores 12 indicate social isolation. The Lubben Social Network Scale-6 has strong internal consistency ( alpha = 0.83) and item reliability. There are no subscales.

    Baseline, 2, 4, 8 months

Secondary Outcomes (8)

  • UCLA Loneliness Scale Short Form

    Baseline, 2, 4, 8 months

  • General Anxiety Disorder

    Baseline, 2, 4, 8 months

  • Patient Health Questionnaire-9

    Baseline, 2, 4, 8 months

  • Multidimensional Scale of Perceived Social Support

    Baseline, 2, 4, 8 months

  • Social Connectedness Scale

    Baseline, 2, 4, 8 months

  • +3 more secondary outcomes

Study Arms (2)

CONNECTED

EXPERIMENTAL

CONNECTED integrates two evidence-based care models--peer support and patient navigation--and involves the delivery of three services by peers: 1) peer support, which includes person-centered assessment for drivers of social isolation; 2) group-based interventions to address Veterans' social isolation and 3) navigation, which involves connecting Veterans to social resources to facilitate social participation. CONNECTED is delivered through individual and group sessions over 8 weeks. All sessions will be delivered via videoconference. Veterans may choose to receive some peer support sessions in person when feasible, to facilitate engagement and retention.

Behavioral: CONNECTED

VET BEFRIENDING

ACTIVE COMPARATOR

VET BEFRIENDING (attention control arm) consists of weekly social interactions with a research assistant (RA). It will match the number of social contacts (12 contacts), frequency (weekly), intervention expectancy (positive treatment expectations), and working alliance (rapport with interventionist) in the intervention arm. The control condition has no overlap with CONNECTED in terms of content and therapeutic elements (e.g., goal setting, navigation).

Behavioral: VET BEFRIENDING

Interventions

CONNECTEDBEHAVIORAL

CONNECTED is a manualized, peer-led, group-based social isolation intervention for diverse veteran populations in VA primary care settings. It is delivered via videoconference through individual and group sessions over 8 weeks.

CONNECTED
VET BEFRIENDINGBEHAVIORAL

VET BEFRIENDING (attention control arm) consists of weekly social interactions with a research assistant (RA) over videoconference or phone.

VET BEFRIENDING

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Eligible participants for Aim 1 \& Aim 2
  • Must be Veterans at the Roudebush Veterans Affairs Medical Center or its Community-Based Outpatient Clinics who had a primary care encounter in the prior 6 months and
  • Veteran obtained a score 12, indicating social isolation, on the Lubben Social Isolation Scale (LSNS-6), a validated, 6-item social isolation measure, at the time of screening in Aim 1.

You may not qualify if:

  • For Aim 1 and Aim 2, the investigators will exclude Veterans with
  • Active suicidal ideation needing immediate mental health treatment
  • severe cognitive, hearing or speech impairment,
  • current exacerbation of severe psychiatric symptoms (e.g., active psychosis), or
  • severe illness that makes study participation not feasible.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Richard L. Roudebush VA Medical Center, Indianapolis, IN

Indianapolis, Indiana, 46202-2884, United States

RECRUITING

MeSH Terms

Conditions

Social Isolation

Interventions

Convolutional Neural Networks

Condition Hierarchy (Ancestors)

Social BehaviorBehavior

Intervention Hierarchy (Ancestors)

Neural Networks, ComputerMathematical Concepts

Study Officials

  • Johanne Eliacin, PhD

    Richard L. Roudebush VA Medical Center, Indianapolis, IN

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Johanne Eliacin, PhD

CONTACT

Carrie Ballard, BA AS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: This is a two-arm, parallel, randomized controlled trial that will enroll 264 Veterans. It will compare the Increasing Veterans' Social Engagement and Connectedness (CONNECTED, intervention arm) to an attention control group (control arm).
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 14, 2024

First Posted

June 20, 2024

Study Start

October 4, 2024

Primary Completion (Estimated)

June 30, 2028

Study Completion (Estimated)

June 30, 2028

Last Updated

July 18, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will share

Publications resulting from the research will be made available to the public through the National Library of Medicine PubMed Central website within one year after the date of publication. Final data sets underlying publications resulting from the research will not be shared outside Veterans Administration, except as required under the Freedom of Information Act. If final data sets under Freedom of Information Act will be shared outside Veterans Administration in electronic format. Final data sets underlying publications resulting from such research will be shared upon request. Final data sets, along with raw data and working data, will be maintained locally on a secure Veterans Administration research network drive behind the Veterans Administration firewall. Data sets based on information obtained from human subjects will be shared as a De-identified, Anonymized Dataset.

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR
Time Frame
The data will become available once the study team completes all analyses.
Access Criteria
Final research datasets underlying all publications reporting results of Veterans Administration research can be made available, upon Freedom of Information Act request.

Locations