Treatment Intervention of Patients With Carpal Tunnel Syndrome (CTS)

NCT06464809 | Completed

• 1 other identifier: CMUH103-REC3-072
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study was to investigate the effectiveness of KT versus TENS combining self-myofascial stretching in treatment of CTS through clinical, functional assessment and sensory measurements. Primary hypothesis The KT group has a more substantial improvement in hand grip, pain relief, enhancing proprioceptive sensitivity and dexterity compare to the TENS group. treatment program,

Conditions

Carpal Tunnel Syndrome

Keywords

Carpal tunnel syndrome; home-based treatment program; kinesio taping; paresthesia; thenar eminence

Outcome Measures

Primary Outcomes (5)

• The SSS and FSS of the Boston Carpal Tunnel Questionnaire (BCTQ)

  Assess symptoms and functional status. The SSS subscale includes 11 items assessing pain, paresthesia, numbness, weakness, nocturnal symptoms and over-all functional status. The FSS subscale includes 8 items assessing the hand function during common daily activities. Each item is scored on a 5-point scale (1-5), from 1(no symptoms) to 5 (the worst symptoms) for SSS, and from 1 (no difficulty) to 5 (cannot perform the activity at all) for FSS. The overall SSS and FSS scores are calculated as the mean of the scores for 11 and 8 individual items respectively, such that the higher the score obtained, the worse the SSS or FSS.

  pre-intervention, 4-week intervention, and 4-week follow-up.

• Hand grip and key pinch strengths

  pinch strength included palmar, three-jaw chuck, tip, and lateral pinches.

  pre-intervention, 4-week intervention, and 4-week follow-up.

• Two-point discrimination (2PD)

  cutaneous sensory perception threshold. The larger the value of distance, the worse the sensory ability.

  pre-intervention, 4-week intervention, and 4-week follow-up.

• Modified Moberg pick-up test (MMPUT)

  hand dexterity. The shorter the time, the more dexterity the hand.

  pre-intervention, 4-week intervention, and 4-week follow-up.

• The visual analog scale (VAS)

  pain measurement. 100 mm straight line, with 0 mm on the far left and 100 mm on the far right, 0 mm positions It is not painful, and 100 mm is extremely painful.

  pre-intervention, 4-week intervention, and 4-week follow-up.

Study Arms (2)

kinesio taping (KT) group

EXPERIMENTAL

Three precut KT I strips with a width of 5 cm were used. The first strip is applied with the subject's wrist in fully extended hand position. Middle and ring fingers through the holes with the base of the tape as anchored to the knuckles, and then the tape was applied with 15%-25% tension covering the palm and the wrist, and the remainder of the tape without any tension from the wrist up to the forearm. The same process is repeated for the second I-strip, which was applied from the dorsum of the hand to wrist while the wrist in a downward flexed position. The final strip was applied to the carpal tunnel region with 25%-35% tension.

Other: kinesio taping (KT)

transcutaneous electrical nerve stimulation (TENS) group

ACTIVE COMPARATOR

A portable TENS unit (Gem-Stim, Gemore Technology Co., LTD. Taiwan) was used, and delivered a bi-phasic symmetric waveform at a continuous frequency of 100 Hz and phase duration of 200 µsec. The intensity was gradually adjusted up to a strong but comfortable l level, as reported by the subject. Two electrodes were placed 2 cm apart, respectively attached to the carpal ligament of the affected side and the proximal end along the direction of the median nerve.

Other: kinesio taping (KT)

Interventions

kinesio taping (KT) OTHER

Also known as: transcutaneous electrical nerve stimulation (TENS)

kinesio taping (KT) group; transcutaneous electrical nerve stimulation (TENS) group

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• numbness and tingling in the median nerve territory of the hand.
• nocturnal paresthesia.
• induction test (Tinel's sign and Phalen's test) showing a positive finding.,
• is defined as mild and moderate CTS according to nerve conduction studies (NCSs).

You may not qualify if:

• is defined severe CTS symptoms.
• are currently pregnant or have any secondary entrapment neuropathy (e.g., diabetes, inflammatory arthritis, hypothyroidism, previous wrist trauma).
• cervical radiculopathy or polyneuropathy.
• previous history of carpal tunnel decompression surgery.
• corticosteroid injection into the carpal tunnel.

Sponsors & Collaborators

• China Medical University Hospital: lead
• Ministry of Science and Technology, Taiwan: collaborator

Study Sites (1)

China Medical University

Taichung, 406040, Taiwan

Location

MeSH Terms

Conditions

Carpal Tunnel Syndrome; Paresthesia

Interventions

Transcutaneous Electric Nerve Stimulation

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries; Somatosensory Disorders; Sensation Disorders; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electric Stimulation Therapy; Therapeutics; Physical Therapy Modalities; Rehabilitation; Analgesia; Anesthesia and Analgesia

Study Officials

• Wei-Hsien Hong, PhD

  China Medical University, Taiwan

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: The participants who met the inclusion criteria were randomized into one of two treatment groups: KT group and TENS group. Participants were blinded to the treatments used in the other group.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: This was a prospective, randomized-controlled trial.

Study Record Dates

• First Submitted: June 4, 2024
• First Posted: June 18, 2024
• Study Start: September 24, 2014
• Primary Completion: November 30, 2015
• Study Completion: December 30, 2015
• Last Updated: June 18, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)