Efficacy of Different Anesthesia Methods in Transbronchial Biopsy

NCT06454513 | Completed

• 1 other identifier: SichuanPPHGZ03
• Study Type: observational
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the efficacy of different anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy using an electronic bronchoscope. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method, operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status.

Conditions

Anesthesia; Respiratory Diseases; Biopsy

Keywords

Anesthesia method; Bronchoscopic biopsy; Efficiency research

Outcome Measures

Primary Outcomes (1)

• Diagnostic efficacy

  The diagnostic positivity rate(%) of transbronchial biopsy under different anesthesia methods between two groups

  baseline

Secondary Outcomes (5)

• Clinical information

  baseline

• lesion location (left/right/other)

  baseline

• lesion size (mm)

  baseline

• Postoperative complications (hemorrhage or pneumothorax）

  baseline

• Operation time

  intraoperative

Study Arms (2)

General anesthesia

There all cases in this group where the surgical anesthesia method is general anesthesia

Procedure: general anesthesia

Local anesthesia

There all cases in this group where the surgical anesthesia method is local anesthesia

Interventions

general anesthesia PROCEDURE

Different anesthesia methods

General anesthesia

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients who require biopsy to further clarify the nature of lung lesions

You may qualify if:

• Completed Transbronchial Biopsy；the platelets count and PT, APTT tests were normal, normal ECG, Anesthesiologist evaluation was needed in General anesthesia group.

You may not qualify if:

• patients with contraindication of bronchoscopy (such as respiratory failure and acute cardio-cerebrovascular events), and women who were pregnant.

Sponsors & Collaborators

• Sichuan Provincial People's Hospital: lead

Study Sites (1)

Sichuan Provincial People's Hospital

Chengdu, Sichuan, 610072, China

Location

MeSH Terms

Conditions

Respiratory Tract Diseases

Interventions

Anesthesia, General

Intervention Hierarchy (Ancestors)

Anesthesia; Anesthesia and Analgesia

Study Officials

• Guanghong G Zhou

  Sichuan Academy of Medical Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Department of Respiratory and Critical Care Medicine

Study Record Dates

• First Submitted: June 6, 2024
• First Posted: June 12, 2024
• Study Start: June 1, 2020
• Primary Completion: June 1, 2024
• Study Completion: June 1, 2024
• Last Updated: June 12, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)