Providing Evidence-Based Approaches for Caregiver Stress Study

NCT06451250 | Completed

• 2 other identifiers: IRB000089191K01AG066812-01
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this preliminary study is to examine the effects of adult day service use on subjective and physiological measures of stress in 50 Black informal caregivers for individuals with dementia (IWD). The PI of the proposed study has substantial training in primary data collection and complex-survey secondary data analysis, she also has the fundamental knowledge to investigate how sociocultural and behavioral factors can influence psychosocial stress. The proposed study will enroll participants from adult day service (ADS) nationally, to examine the effects of adult day service use on subjective and physiological measures of stress in 50 Black informal caregivers. The proposed study extends the current science on the use of ADS on subjective and physiological stress by 1) examining differential impacts of ADS specifically on subjective measures of stress for Black caregivers, 2) evaluating the impact of ADS use on physiological measures of stress among Black caregivers; and 3) examining the relationship between subjective indicators and physiological processes for Black caregivers.

Conditions

Caregiving Stress; Dementia

Outcome Measures

Primary Outcomes (1)

• Caregiver stress as assessed by the Perceived Stress Scale

  Perceived Stress Scale scores range from 0 to 40 with higher scores indicating higher perceived stress

  Baseline

Secondary Outcomes (3)

• Salivary cortisol levels

  Over a five day period

• Salivary alpha-amylase

  Over a five day period

• Salivary Telomere length

  Over a five day period

Study Arms (1)

Adult Day Services

EXPERIMENTAL

Adult Day Service use for family member with dementia

Other: Adult Day Service use for family member with dementia

Interventions

Adult Day Service use for family member with dementia OTHER

Self-collection of salivary biomarkers 4 times daily for 5 days, two of those days the family member with dementia has to use adult day services

Adult Day Services

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years or older (male or female)
• Self-identify as Black and/or African American,
• Lives with a family member with a physician diagnosis of Alzheimer's disease or related dementia
• Primary responsibility for care of the family member who has been diagnosed with Alzheimer's disease or related dementia
• Utilize Adult Day Services at least two times a week for family member with Alzheimer's disease or related dementia

You may not qualify if:

• Either caregiver of client is in active treatment for a terminal illness or are in hospice.

Sponsors & Collaborators

• Johns Hopkins Bloomberg School of Public Health: lead
• National Institute on Aging (NIA): collaborator

Study Sites (1)

Johns Hopkins University

Baltimore, Maryland, 21205, United States

Location

MeSH Terms

Conditions

Caregiver Burden; Dementia

Condition Hierarchy (Ancestors)

Stress, Psychological; Behavioral Symptoms; Behavior; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders

Study Officials

• Lauren Parker, PhD, MPH

  Johns Hopkins Bloomberg School of Public Health

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 5, 2024
• First Posted: June 11, 2024
• Study Start: February 2, 2024
• Primary Completion: December 19, 2025
• Study Completion: December 19, 2025
• Last Updated: December 24, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)