Trials Sponsors Conditions Drugs Pricing

Conditions

Acute Myocardial Infarction Hemorrhagic Myocardial Infarction Myocardial Hemorrhage Myocardial Reperfusion Injury Myocardial Rupture (Post Infarct)Myocardial Stunning

Outcome Measures

Primary Outcomes (3)

Wall Strain Index for Potential Detection of Intramyocardial Hemorrhage
Difference in Wall Strain Index values between patients with intramyocardial hemorrhage and those without, confirmed by cardiac MRI.
48 hours Post-PCI
Wall Strain Index in Detecting the Severity of Intramyocardial Hemorrhage
Relationship between initial Wall Strain Index measurements and the volume of intramyocardial hemorrhage quantified by cardiac MRI
48 hours Post-PCI
Wall Strain Index Ratio in Identification of Vulnerable LV Segments for Cardiac Rupture
Wall Strain Index Ratio for circumferential and longitudinal strain in identifying vulnerable hemorrhagic left ventricular segments at risk for rupture

Eligibility Criteria

Age18 Years - 79 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

The study population consists of individuals aged 18 to 80 who have been diagnosed with acute ST-elevation myocardial infarction (STEMI) and are scheduled for emergency percutaneous coronary intervention (PCI).

You may qualify if:

Index STEMI

Sponsors & Collaborators

Rohan Dharmakumar
Otherlead

Study Sites (1)

Krannert Cardiovascular Research Center, Indiana University School of Medicine

Indianapolis, Indiana, 46202, United States

MeSH Terms

Conditions

Myocardial StunningMyocardial Reperfusion InjuryHeart Rupture, Post-Infarction

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsCardiomyopathiesMyocardial IschemiaVascular DiseasesReperfusion InjuryPostoperative ComplicationsPathologic ProcessesHeart Rupture

Study Officials

Rohan Dharmakumar, PhD
Indiana University
STUDY DIRECTOR
Keyur P Vora, MD FACC
Indiana University
PRINCIPAL INVESTIGATOR

Enrollment

250 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Executive Director, Krannert Cardiovascular Research Center

Study Record Dates

First Submitted

June 4, 2024

First Posted

June 10, 2024

Study Start

June 1, 2022

Actual (reported)

Novel Imaging Biomarkers for Mechanical Complications in Acute Myocardial Infarction

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (3)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (3)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations