The Open Kinetic Chain and Closed Kinetic Chain Strengthening Exercises in Degenerative Meniscus Tears

NCT06447142 | Completed

• 1 other identifier: 2133
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized-controlled trial aims to compare the effect of open kinetic chain and closed kinetic chain strengthening exercises on pain, function, and health-related quality of life in degenerative meniscus tears.

Conditions

Degenerative Disease; Meniscus Tear; Knee Pain Swelling

Outcome Measures

Primary Outcomes (1)

• Knee Injury and Osteoarthritis Outcome Score (KOOS)

  Short-term and long-term symptoms and function will be assessed with the Knee injury and Osteoarthritis Outcome Score (KOOS) that is developed as an extension of the WOMAC Osteoarthritis Index. The score is a percentage score from 0 to 100, 0 representing extreme problems and 100 representing no problems.

  Baseline

Secondary Outcomes (11)

• Knee Injury and Osteoarthritis Outcome Score (KOOS)

  At the end of 8-week intervention

• Visual Analogue Scale (VAS)

  Baseline

• Visual Analogue Scale (VAS)

  At the end of 8-week intervention

• Active Range of Motion

  Baseline

• Active Range of Motion

  At the end of 8-week intervention

Study Arms (2)

Open Kinetic Chain Exercise Group

EXPERIMENTAL

Each subject in Open Kinetic Chain Exercise Group will receive a treatment protocol consisting of stretching exercises, open kinetic chain strengthening exercises, and functional exercises for the knee and hip.

Other: Open kinetic chain strengthening exercise

Closed Kinetic Chain Exercise Group

ACTIVE COMPARATOR

Each subject in Closed Kinetic Chain Exercise Group will receive a treatment protocol consisting of stretching exercises, closed kinetic chain strengthening exercises, and functional exercises for the knee and hip.

Other: Closed kinetic chain strengthening exercise

Interventions

Open kinetic chain strengthening exercise OTHER

A web-based 8-week exercise program consisting of stretching exercises, open kinetic chain strengthening exercises, and functional exercises for the knee and hip will be performed.

Open Kinetic Chain Exercise Group

Closed kinetic chain strengthening exercise OTHER

A web-based 8-week exercise program consisting of stretching exercises, closed kinetic chain strengthening exercises, and functional exercises for the knee and hip will be performed.

Closed Kinetic Chain Exercise Group

Eligibility Criteria

• Age: 35 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being aged between 35 and 65 years
• Having the degenerative meniscus tear in at least one knee
• Having body mass index in the range of 18-30 kg/m2
• Feeling the pain that lasts for at least 2 months
• Having grade 1 or grade 2 degenerative meniscal tear diagnosed by an orthopedic specialist according to the MRI results
• Access to the internet via a computer or smartphone
• Ability to read and write in Turkish

You may not qualify if:

• Having undergone arthroscopic partial meniscectomy surgery due to degenerative meniscal tear
• Participating in a physiotherapy program for degenerative meniscal tear in the last 12 weeks
• Have received steroid injections in the last 6 months
• Accompanying conditions such as injury to the surrounding ligaments, congenital anomaly in the affected knee, coxarthrosis and spinal stenosis
• Presence of any systemic disorder that may affect assessment parameters
• Any health condition that may prevent participation in physical activity or an exercise program (e.g., severe cardiovascular, respiratory, neurological, or musculoskeletal disorders)
• Failure to cooperate with assessments

Sponsors & Collaborators

• Istanbul University - Cerrahpasa: lead

Study Sites (1)

Istanbul University-Cerrahpasa

Istanbul, Bakırkoy, 34147, Turkey (Türkiye)

Location

Study Officials

• Tansu Birinci, PT, PhD

  Istanbul University - Cerrahpasa

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 3, 2024
• First Posted: June 6, 2024
• Study Start: June 10, 2024
• Primary Completion: October 25, 2024
• Study Completion: January 10, 2025
• Last Updated: June 13, 2025

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)