Pilot Study for the Early Detection of Chronic Kidney Disease, Non-Dialysis Objective (NDO).

NCT06447038 | Enrolling By Invitation DMC

• 1 other identifier: OND 01
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic kidney disease (CKD) is a significant public health problem worldwide, affecting more than 10% of the Spanish population. Early detection is considered a top healthcare priority to establish strategies for preventing progression to more advanced stages of the disease and its complications. Additionally, CKD is associated with high comorbidity, poor prognosis, and substantial resource consumption within the healthcare system. In this context, albuminuria may be a more sensitive marker of CKD than reduced glomerular filtration rate (GFR), and it is also considered an indicator of not only renal damage but also \"systemic damage\" (generalized endothelial dysfunction, arterial remodeling, and increased cardiovascular risk) beyond the kidney. Furthermore, the reduction of proteinuria/albuminuria is clearly associated with a slower progression of CKD, making its reduction a therapeutic goal as well. Given this importance, this protocol aims to determine the urine albumin/creatinine ratio in all patients over 18 years old who visit their primary care physician in the province of Burgos, Spain, and require a blood test related to their reason for consultation.

Conditions

Chronic Kidney Disease (CKD)

Keywords

Epidemiology.; Chronic kidney disease.; Primary care.; Cardiovascular risk factors.

Outcome Measures

Primary Outcomes (1)

• Albumin creatinine ratio.

  Determination of albuminuria in urine.

  01/02/2024 al 01/12/2024

Study Arms (1)

Population

Population of the city of Burgos \> 18 years old.

Diagnostic Test: albumin creatinine ratio

Interventions

albumin creatinine ratio DIAGNOSTIC_TEST

Albumin creatinine ratio, this test is routinely performed in urine.

Population

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Population of the city of Burgos, Spain who go to their primary doctor.

You may qualify if:

• Minimum age 18 years

You may not qualify if:

• Age less than 18 years

Sponsors & Collaborators

• Hospital Universitario de Burgos: lead

Study Sites (1)

Maria J Izquierdo

Burgos, 09003, Spain

Location

Related Publications (1)

• Webster AC, Nagler EV, Morton RL, Masson P. Chronic Kidney Disease. Lancet. 2017 Mar 25;389(10075):1238-1252. doi: 10.1016/S0140-6736(16)32064-5. Epub 2016 Nov 23.

  PMID: 27887750 BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Maria J Izquierdo Ortiz, Doctor

  HUBU

  STUDY DIRECTOR

• Emilio J Gonzalez Parra, Doctor

  HUBU

  PRINCIPAL INVESTIGATOR

• Sebastian Mas Fontao, Doctor

  HUBU

  PRINCIPAL INVESTIGATOR

• Maria Martin Palencia, Doctor

  HUBU

  PRINCIPAL INVESTIGATOR

• Didier Sanchez, Doctor

  HUBU

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Target Duration: 10 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor investigator

Study Record Dates

• First Submitted: June 3, 2024
• First Posted: June 6, 2024
• Study Start: February 1, 2024
• Primary Completion: October 1, 2024
• Study Completion: December 1, 2024
• Last Updated: June 6, 2024

Record last verified: 2024-06

Locations

ES (1)