NCT06446791

Brief Summary

The webbed neck is one of the conspicuous deformities of Turner syndrome that presents a surgical challenge. Despite the availability of surgical techniques, surgical outcomes are not always acceptable and recurrence occurs. Mehri Turki performed a surgical technique based on a latéral cervical approach allowing direct visual control to manage the fibrotic band. It provides a high level of visual control so that vulnerable anatomic structures are easily protected.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2008

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 27, 2008

Completed
7.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 22, 2015

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 24, 2017

Completed
7.3 years until next milestone

First Submitted

Initial submission to the registry

May 24, 2024

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 6, 2024

Completed
Last Updated

June 7, 2024

Status Verified

June 1, 2024

Enrollment Period

7.8 years

First QC Date

May 24, 2024

Last Update Submit

June 6, 2024

Conditions

Keywords

Congenital abnormalitiesWebbed neckSurgical techniqueTurner syndromeFetal cystic hygromaNuchal fold

Outcome Measures

Primary Outcomes (3)

  • Neck contour

    Number of patient obtaining a normal neck contour without lateral fold

    Just at the postoperative outcome up to 24 months of follow-up

  • Posterior hairline placement

    Number of patients with posterior hairline assent

    Just at the postoperative outcome up to 24 months of follow-up

  • Scars placement

    Number of patients with a placement of scars at the level of the hairline

    Just at the postoperative outcome up to 24 months of follow-up

Secondary Outcomes (2)

  • Scars quality

    from 8 months up to 24 months

  • Recurrece of the fold

    24 months

Study Arms (1)

Single arm interventionnal study

OTHER

A lateral approach surgical technique for the treatment of the webbed neck.

Procedure: Mehri Turki Surgical Technique of the Webbed Neck

Interventions

The incision was made at the junction of the hairless skin and the hairy skin from the mastoid up to the acromion. A subcutaneous undermining allows direct visual control to excise the fibrotic band. Then the hairy skin with a triangular shape was excised. The closure of the defect was done after undermining an anterior cervical flap which was translated in a posterosuperior direction. Z plasty was performed in front of the acromion to prevent scar contracture. Surgical scars are concealed in the hairline which was well placed. The same procedure is done at the same surgical field on the other side to achieve perfect symmetry.

Also known as: Mehri Turki Lateral approach Technique for the webbed beck
Single arm interventionnal study

Eligibility Criteria

Age17 Years - 19 Years
Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • webbed neck with abnormal hairline

You may not qualify if:

  • Surgical contraindication for any health concern
  • Puberty age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Mehri Turki I. Surgical correction of the webbed neck: an alternative lateral approach. GMS Interdiscip Plast Reconstr Surg DGPW. 2017 Mar 2;6:Doc04. doi: 10.3205/iprs000106. eCollection 2017.

  • Turki IM. Surgical techniques for the webbed neck: a narrative review with a comparative study and surgical decision-making algorithm for an optimal aesthetic result. Oral Maxillofac Surg. 2024 Jun;28(2):469-484. doi: 10.1007/s10006-023-01166-2. Epub 2023 Jun 20.

Related Links

MeSH Terms

Conditions

Congenital AbnormalitiesTurner SyndromeNuchal bleb, familial

Condition Hierarchy (Ancestors)

Congenital, Hereditary, and Neonatal Diseases and AbnormalitiesGonadal DysgenesisDisorders of Sex DevelopmentUrogenital AbnormalitiesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesSex Chromosome Disorders of Sex DevelopmentMale Urogenital DiseasesHeart Defects, CongenitalCardiovascular AbnormalitiesCardiovascular DiseasesHeart DiseasesSex Chromosome DisordersChromosome DisordersGenetic Diseases, InbornGonadal DisordersEndocrine System Diseases

Study Officials

  • Imen Mehri Turki

    University Hospital Mohamed Tahar Maamouri. Nabeul, Tunisia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: Girls with congenital webbed neck deformity underwent the same surgical technique. Outcomes were analysed with long-term follow-up.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Maxillofacial and aesthetic surgeon

Study Record Dates

First Submitted

May 24, 2024

First Posted

June 6, 2024

Study Start

January 27, 2008

Primary Completion

November 22, 2015

Study Completion

January 24, 2017

Last Updated

June 7, 2024

Record last verified: 2024-06