Public Perception and Policy for SARS-CoV-2 Whole Genome Sequencing and Genomics for All

NCT06441981 | Recruiting

• 1 other identifier: WGS Project
• Study Type: interventional
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

Gap in understanding undermines government and public support for SC2-WGS, and other wide-scale genomic sequencing (Gut microbiome, Genome Wide Sequencing for Prenatal Detection, Tuberculosis Metagenomic sequencing, Nutrigenetics and Cancer Next Generation Sequencing) as a routine part of the pandemic response, especially in low- and middle-income countries. However, such gaps can be closed with systematic efforts to define and measure specific misperceptions, and subsequently design and use targeted messages and promotional materials. We propose here in the following specific aims to first determine the entire set of beliefs and emotions regarding SC2-WGS and other genomic sequencing (Gut microbiome, Genome Wide Sequencing for Prenatal Detection, Tuberculosis Metagenomic sequencing, Nutrigenetics and Cancer Next Generation Sequencing), then identify and measure limiting belief constructs, and then create social media and communication media to address and overcome limiting beliefs strategically. The goal is to increase public and policymaker support for SC2-WGS and other genomic sequencing (Gut microbiome, Genome Wide Sequencing for Prenatal Detection, Tuberculosis Metagenomic sequencing, Nutrigenetics and Cancer Next Generation Sequencing) resources and actions for pandemic control.

Conditions

Knowledge, Attitudes, Practice

Keywords

Genome Sequencing; Public Perception; Public Policy; COVID-19

Outcome Measures

Primary Outcomes (1)

• Knowledge

  Assessment of respondents' knowledge regarding the educational material provided, calculated based on the number of questions answered correctly.

  2 months

Study Arms (1)

Behavioral Education

OTHER

Educational material is provided via WhatsApp chatbot. After being educated, respondents were given a test to determine the increase in understanding of the material.

Behavioral: Education

Interventions

Education BEHAVIORAL

Educational material brochures will be given to 800 respondents. Educational material is provided via WhatsApp chatbot. After being educated, respondents were given a test to determine the increase in understanding of the material.

Behavioral Education

Eligibility Criteria

• Age: 21 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Living or working in Jakarta
• Young adult
• Adult
• Elderly
• Health workers
• Public Policy

You may not qualify if:

• \- Living or working outside Jakarta

Sponsors & Collaborators

• Indonesia University: lead
• Oxford University Clinical Research Unit: collaborator

Study Sites (1)

Department of Nutrition (FKUI-RSCM); and Human Nutrition Research Center, Indonesian Medical Education Research Institute (HNRC-IMERI) Faculty of Medicine, Universitas Indonesia

Jakarta Pusat, DKI Jakarta, 10430, Indonesia

RECRUITING

Related Publications (2)

• Schumann S, Gschmeidler B, Pellegrini G. Knowing, relationships and trust-citizens' perceptions of whole genome sequencing for the Genetics Clinic of the Future. J Community Genet. 2021 Jan;12(1):67-80. doi: 10.1007/s12687-020-00486-0. Epub 2020 Sep 30.

  PMID: 32997319 BACKGROUND

• Lewis KL, Han PK, Hooker GW, Klein WM, Biesecker LG, Biesecker BB. Characterizing Participants in the ClinSeq Genome Sequencing Cohort as Early Adopters of a New Health Technology. PLoS One. 2015 Jul 17;10(7):e0132690. doi: 10.1371/journal.pone.0132690. eCollection 2015.

  PMID: 26186621 BACKGROUND

Related Links

• Re-Thinking Science: Knowledge and the Public in an Age of Uncertainty

MeSH Terms

Conditions

Behavior; COVID-19

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Socioeconomic Factors; Population Characteristics

Study Officials

• Rina Agustina

  https://imeri.fk.ui.ac.id

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rina Agustina

CONTACT

+622129189160; r.agustina@ui.ac.id

Rahyussalim Rahyussalim

CONTACT

+622129189160; manajer.riset.fkui1@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: The questionnaire in whatsapp chatbot format will be given to 100 and up to 200 persons from each targeted population. There Four targeted population namely, The public overall (comprised mostly of 18-29 years old adults whom have the most cases), Vulnerable groups (including the elderly between 50-80 years old, parents of children 0-12 years, and pregnant women), Doctors and other frontline health workers, and Program implementers and policy makers.

Study Record Dates

• First Submitted: May 31, 2024
• First Posted: June 4, 2024
• Study Start: October 1, 2023
• Primary Completion: October 31, 2024
• Study Completion: December 30, 2024
• Last Updated: June 4, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

ID (1)