NCT06438926

Brief Summary

Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited. This malposition allows for prolonged food accumulation, bacterial and plaque retention, which are important factors for the initiation and progression of dental caries.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
325

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2024

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 20, 2024

Completed
14 days until next milestone

First Posted

Study publicly available on registry

June 3, 2024

Completed
3 months until next milestone

Study Start

First participant enrolled

September 1, 2024

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2025

Completed
Last Updated

June 3, 2024

Status Verified

May 1, 2024

Enrollment Period

1 year

First QC Date

May 20, 2024

Last Update Submit

May 27, 2024

Conditions

Caries

Outcome Measures

Primary Outcomes (1)

  • Dental Caries

    DMF index developed by WHO health organization using numbered scores

    throughout study completion an average of 1 year

Eligibility Criteria

Age12 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Young adults range from 12-30 years,Females or Males with anterior dental crowding.

You may qualify if:

  • Young adults range from 12-30 years.
  • Females or Males.
  • Anterior dental crowding.

You may not qualify if:

  • Patients undergoing orthodontic treatment.
  • Patients who have any missing anterior teeth.
  • Patients who have any physical or mental disabilities.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Hafez HS, Shaarawy SM, Al-Sakiti AA, Mostafa YA. Dental crowding as a caries risk factor: a systematic review. Am J Orthod Dentofacial Orthop. 2012 Oct;142(4):443-50. doi: 10.1016/j.ajodo.2012.04.018.

    PMID: 22999666BACKGROUND

  • Caplin JL, Evans CA, Begole EA. The Relationship between Caries and Malocclusion in Chinese Migrant Workers' Children in Shanghai. Chin J Dent Res. 2015;18(2):103-10.

    PMID: 26167548BACKGROUND

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

May 20, 2024

First Posted

June 3, 2024

Study Start

September 1, 2024

Primary Completion

September 1, 2025

Study Completion

November 1, 2025

Last Updated

June 3, 2024

Record last verified: 2024-05