Handwriting Analysis in Movement Disorders.

NCT06436287 | Not Yet Recruiting

• 1 other identifier: 123953
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Movement disorders are a group of neurological conditions that cause problems with movement, either in the form of excessive, reduced, or slow movements. Some commonly known movement disorders include Parkinson disease, dystonia, ataxia, and Tourette syndrome. Multiple movement disorders have unique handwriting characteristics that can be measured using an inkless pen and a digitalized tablet. Handwriting is a complex skill that requires a combination of cognition, motor planning, and visuomotor integration. Handwriting deteriorates in patients with neurodegenerative diseases. This study aims to discern variations in the kinematics (movement patterns) involved in handwriting between individuals with movement disorders and healthy controls. Participants will be invited to carry out a series of handwriting tasks. The pen motions will be captured using an inkless pen and a digitizing tablet linked to a laptop. The entire set of tasks is designed to be completed within 30 minutes. The data will then be collected, processed, and analyzed utilizing a handwriting analysis software.

Conditions

Movement Disorders

Outcome Measures

Primary Outcomes (1)

• Primary handwriting kinematic parameter (velocity)

  Average absolute vertical velocity (cm/s)

  Day 1

Secondary Outcomes (3)

• Secondary handwriting kinematic parameter (acceleration)

  Day 1

• Secondary handwriting kinematic parameter (duration)

  Day 1

• Pen pressure

  Day 1

Study Arms (2)

Cases

Diagnosed with a movement disorder

Control

Healthy controls

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Movement disorder patients will be recruited from the London Movement Disorder Clinic.

You may qualify if:

• (1) Diagnosed with a movement disorder.

You may not qualify if:

• Action tremor or weakness in the dominant hand interfering with writing task.
• Unable to write or understand English

Sponsors & Collaborators

• Western University, Canada: lead

Study Sites (1)

Aditya Murgai

London, Ontario, N6A5A5, Canada

Location

MeSH Terms

Conditions

Movement Disorders

Condition Hierarchy (Ancestors)

Central Nervous System Diseases; Nervous System Diseases

Central Study Contacts

Aditya Murgai

CONTACT

519-685-8500; aditya.murgai@lhsc.on.ca

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor in Neurology

Study Record Dates

• First Submitted: May 6, 2024
• First Posted: May 31, 2024
• Study Start: January 1, 2025
• Primary Completion (Estimated): July 1, 2029
• Study Completion (Estimated): July 1, 2030
• Last Updated: January 24, 2025

Record last verified: 2025-01

Locations

CA (1)