Predictive Value of Combining AccuIMR and AccuFFR in Patients With STEMI
1 other identifier
observational
1,297
1 country
1
Brief Summary
Patients with acute myocardial infarction were enrolled retrospectively. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were analyzed, and the relationship between FFR and IMR and the prognosis of patients with acute myocardial infarction was analyzed
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2024
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 30, 2024
CompletedFirst Submitted
Initial submission to the registry
May 26, 2024
CompletedFirst Posted
Study publicly available on registry
May 30, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
May 30, 2024
CompletedMay 30, 2024
May 1, 2024
2 months
May 26, 2024
May 26, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
MACE
cardiovascular death, all-cause death, readmission for heart failure (HF), and recurrent coronary events
3 years after myocardial infarction
Secondary Outcomes (1)
recurrent coronary events
3 years after myocardial infarction
Study Arms (1)
STEMI
Patients with STEMI who underwent primary PCI and were hospitalized at Peking University Third Hospital between January 2017 and March 2022
Interventions
AccuFFR and AccuIMR were obtained by reviewing coronary angiography at the time of primary PCI
Eligibility Criteria
Patients with STEMI who underwent primary PCI and were hospitalized at Peking University Third Hospital between January 2017 and March 2022.
You may qualify if:
- Age of \>18 years;
- Onset-to-treatment time of ≤12 h, meeting the diagnostic criteria for STEMI;
- underwent primary PCI within 12 h of symptom onset and achieved successful PCI in the culprit vessel;
- Availability of complete clinical data
You may not qualify if:
- severe tortuosity and overlap of the target vessel;
- poor-quality coronary angiography images;
- missing two coronary angiography images \>25° apart
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Peking University Third Hospital
Beijing, China
Related Publications (1)
Li J, Xie P, Hu Y, Zhou Y, Zhao W, Xu X, Zhu D, Mi L, Xiang J, Cui M. Predictive Value of Combining Angio-Based Index of Microcirculatory Resistance and Fractional Flow Reserve in Patients with STEMI. Can J Cardiol. 2025 Jul;41(7):1363-1371. doi: 10.1016/j.cjca.2025.02.003. Epub 2025 Feb 6.
PMID: 39922306DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Ming Cui, Dorctor
Peking University Third Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 26, 2024
First Posted
May 30, 2024
Study Start
March 1, 2024
Primary Completion
April 30, 2024
Study Completion
May 30, 2024
Last Updated
May 30, 2024
Record last verified: 2024-05
Data Sharing
- IPD Sharing
- Will not share