Social History and Glaucoma Progression

NCT06434155 | Completed DMC

• 1 other identifier: 17200545
• Study Type: observational
• Target: 1,584
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to predict of glaucoma progression. By imaging of the retinal nerve fiber layer RNFL, optic nerve head (ONH) and macular measurements using spectral-domain OCT (SD-OCT) instruments

Conditions

Glaucoma Open-Angle

Keywords

Glaucoma; OCT

Outcome Measures

Primary Outcomes (1)

• OCT structural parameters

  RNFL in (um), ONH in (um), as well as the inner macula thickness (in um) using spectral domain OCT

  6 months

Study Arms (1)

Primary Open Angle Glaucoma

1. Patients older than 18 years of age with primary open-angle glaucoma (POAG) 2. POAG diagnosed on the basis of IOP measurements more than 21 mmHg, Open angle on gonioscopy (Grade 3 or 4 on Schaffer grading system for angle width), glaucomatous visual field defects consistent with glaucomatous optic disc changes. 3. Eyes with baseline macular and ONH OCT images and ONH photographs of adequate quality and r performed within 6 months of each other were selected

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients older than 18 years of age with primary open-angle glaucoma (OAG)

You may qualify if:

• IOP measurements more than 21 mmHg
• Open angle on gonioscopy (Grade 3 or 4 on Schaffer grading system for angle width)
• Glaucomatous visual field defects consistent with glaucomatous optic disc changes.
• Eyes with baseline macular and ONH OCT images and ONH photograps

You may not qualify if:

• Participants with significant retinal disease.
• non-glaucomatous optic neuropathy.
• anomalous discs
• any retinal pathology.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Faculty of Medicine

Asyut, 71515, Egypt

Location

MeSH Terms

Conditions

Glaucoma, Open-Angle; Glaucoma

Condition Hierarchy (Ancestors)

Ocular Hypertension; Eye Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: May 20, 2024
• First Posted: May 30, 2024
• Study Start: January 1, 2022
• Primary Completion: July 1, 2022
• Study Completion: July 1, 2022
• Last Updated: May 30, 2024

Record last verified: 2024-05

Locations

EG (1)