Rate of Canine Retraction and Pain Perception Following Micro-osteoperforation- a Split Mouth Clinical Study

NCT06432699 | Completed

• 1 other identifier: FF/FUMC/215-372Phy/23
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

DEFINITION: A short description of clinical study , including a brief statement of clinical study's hypothesis, written in language intended for the lay public Limit: 5000 CHARACTERS

Conditions

Pain; Rate of Canine Retraction

Keywords

MOP

Outcome Measures

Primary Outcomes (1)

• pain will be measured after intervention of visual analogue scale

  patient after undergoing micro-osteoperforation will be aske to measure pain and check rate of canine retraction

  three months since the MOPS

Study Arms (2)

Control

NO INTERVENTION

Participants in this arm will receive no MOP treatment

Experimental

EXPERIMENTAL

participants in this arm will receive MOPS intervention

Other: micro osteoperforation

Interventions

micro osteoperforation OTHER

one side used for mops while other side will be control in same patient

Also known as: Placebo/Controlled

Experimental

Eligibility Criteria

• Age: 14 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• \- 1. Age range around 15-40 years. 2. Patients which have class I malocclusion or class II Div I malocclusion and include first premolar extraction as part of treatment plan..
• \. No orthodontic treatment previously 4. Radiographic evidence showing no bone loss 5. History showing no periodontal disease. 6. History showing no systemic disease. 7. Probing depth less than 4 mm across the entire dentition 8. No active carious lesion or any sign of gingivitus

You may not qualify if:

• Presence of any craniofacial abnormality.
• Any history of bleeding disorders.
• Poor oral hygiene.
• Use of bisphosphonates, analgesics, anti-inflammatory drugs, corticosteroids for more than three months prior to treatment or during treatment.
• Active diseases such as metabolic bone disease.
• Malocclusions requiring surgical intervention.
• Smoker

Sponsors & Collaborators

• Foundation University Islamabad: lead

Study Sites (1)

Foundation University Islamabad

Islamabad, Punjab Province, 04403, Pakistan

Location

Related Publications (1)

• 1. Kundi, I., Alam, M. K., & Shaheed, S. (2020). Micro-osteo perforation effects as an intervention on canine retraction. The Saudi dental journal, 32(1), 15-20. https://doi.org/10.1016/j.sdentj.2019.05.009 2. Husain S, Sundari S. Comparison of the effectiveness of piezocision-aided canine retraction augmented with micro-osteoperforation: a randomized controlled trial. Angle Orthod. 2023 Oct 16. doi: 10.2319/052323-370.1. Epub ahead of print. PMID: 37839802. 12 3. Aboalnaga AA, Aboalnaga AA, Salah Fayed MM, El-Ashmawi NA, Soliman SA. Effect of micro-osteoperforation on the rate of canine retraction: a split- mouth randomized controlled trial. Prog Orthod. 2019 Jun;20(1) 21. doi:10.1186/s40510-019-0274-0. PMID: 31155698; PMCID: PMC6545296. 4. Bolat Gümüş, E., Kınsız, E. Effects of miniscrew-facilitated micro- osteoperforations on the rate of orthodontic tooth movement. J Orofac Orthop 84 (Suppl 2), 104-110 (2023). 5. Martina K., Kumar P., Misra V., Attri S., Yadav A., Sam R., Kumar R.. To evaluate the rate of canine retraction and pain perception following micro- osteoperforation - a split-mouth clinical study. Australasian Orthodontic Journal. 2022;38(2): 388-395

  BACKGROUND

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Participants will be randomly assigned to receive Micro-osteoperforation and the other side will be control.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: ZAINAB BUTT

Model Details: This is a single-blind, randomized parallel-arm study with two arms. Participants will be randomly assigned to either MOPS or no Mops

Study Record Dates

• First Submitted: May 23, 2024
• First Posted: May 29, 2024
• Study Start: May 1, 2024
• Primary Completion: July 30, 2024
• Study Completion: December 30, 2024
• Last Updated: January 27, 2025

Record last verified: 2024-06

Locations

PA (1)