Cerebrolysin in SAH (Subarachnoidal Haemorrhage) - Observational Study

NCT06429943 | Completed

• 1 other identifier: SAH/2020/2023
• Study Type: observational
• Target: 47
• Locations: 1 country
• Sites: 1

Brief Summary

Subarachnoid haemorrhage often affects people in middle age and is associated with high mortality or neurological damage. In recent years, advances in surgical techniques have im-proved the mortality rate. However, there is still need for the research for the optimal possible final effect of treatment. In our study, we've decided to examine the effect of a multimodal approach including Cerebrolysin in the supportive treatment of patients. We've examined the supply of neuroprotective drugs and neuromonitoring.

Conditions

SAH (Subarachnoid Hemorrhage)

Keywords

SAH; Cerebrolysin; neuromonitoring

Outcome Measures

Primary Outcomes (1)

• GOS Glasgow Outcome Scale

  Glasgow Outcome Scale - 5 points scale, characterizing the patients' deficits

  1 month

Secondary Outcomes (2)

• LOS Length of Stay

  hospitalisation time

• mortality

  1 month

Study Arms (2)

A

Cerebrolysin administration

B

without Cerebrolysin administration

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population is the population of patients diagnosed with SAH, treated in University Hospital no.1 in Szczecin, Poland. Mainly the patients come from the population of westerpomeranian county, but as SAH is an acute disease also patients from the whole region of Poland, treated in the Hospital were included in the study.

You may qualify if:

• age \>18 years old, diagnosis of SAH, treatment in ICU conditions

You may not qualify if:

• age \<18 years, medical history of allergy to Cerebrolysin, acute renal failure, pregnancy, multi organ trauma, death within 48 hours after admission

Sponsors & Collaborators

• Pomeranian Medical University Szczecin: lead

Study Sites (1)

Pomeranian Medical University, University Hospital no.1

Szczecin, Poland

Location

MeSH Terms

Conditions

Subarachnoid Hemorrhage

Condition Hierarchy (Ancestors)

Intracranial Hemorrhages; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 21, 2024
• First Posted: May 28, 2024
• Study Start: January 15, 2021
• Primary Completion: October 15, 2022
• Study Completion: January 10, 2023
• Last Updated: May 28, 2024

Record last verified: 2023-12

Locations

PL (1)