Prevalence and Management Practice of Diabetic Kidney Disease at BADAS Affiliated Healthcare Centres in Bangladesh

NCT06422598 | Recruiting

• 1 other identifier: BADAS-ERC/EC/24/23
• Study Type: observational
• Target: 320
• Locations: 1 country
• Sites: 8

Brief Summary

Background: Diabetes is a growing public health concern in Bangladesh, with millions affected. Diabetic Kidney Disease (DKD) is a severe complication of diabetes, affecting approximately 21.3% of the diabetic population. To address this issue, a comprehensive assessment of DKD within the Bangladesh Diabetic Association\'s (BADAS) affiliated healthcare centres is necessary. Objective: The study\'s general objective is to determine the prevalence of DKD and evaluate its management at BADAS-affiliated healthcare centers. Specific objectives include assessing risk factors, screening practices, disease staging, management approaches, patient education, and providing evidence-based recommendations. Methodology:

• Study Design: Cross-sectional
• Study Population: All diabetic patients at BADAS-affiliated centers
• Exclusion Criteria: Patients unwilling to participate or with kidney disease from other causes and with acute illness
• Sample Size: \"Forty patients will be selected from each center, resulting in a total sample size of 320 patients across eight centers, with one center randomly selected from each of the eight divisions in Bangladesh.\"
• Data Collection: Demographics, comorbidities, kidney function, blood pressure, HbA1c levels, medication records, treatment guideline adherence
• Data Analysis: prevalence of diabetic kidney disease, factors affecting management, and potential barriers
• Ethical Considerations: Ensure patient data privacy, obtain approvals, and informed consent Implications: The study aims to provide insights into the current state of magnitude (prevalence) of DKD, its management, highlighting areas for improvement in patient care, guideline adherence, and ultimately enhancing the well-being of diabetic patients in Bangladesh.

Conditions

Diabetic Kidney Disease

Keywords

diabetes; Diabetic kidney disease; Prevalence; management

Outcome Measures

Primary Outcomes (1)

• Prevalence of diabetic kidney disease

  Calculate the prevalence of DKD among diabetic patients visiting BADAS-affiliated healthcare centers using clinical and laboratory assessments.

  Day 1

Secondary Outcomes (3)

• Risk Factors for DKD

  Day 1

• Screening Practices

  Day 1

• Management Approaches

  Day 1

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

We will select forty patients from each centre, resulting in a total sample size of 320 patients across eight centres, with one centre will be randomly selected from each of the eight divisions in Bangladesh

You may qualify if:

• All registered diabetic patients receiving care at affiliated healthcare centres of Bangladesh Diabetic Associations.

You may not qualify if:

• Unwilling to participate in the study.
• Presence of AKI or acute illness
• Presence of Known kidney disease due to other cause.
• Pregnancy

Sponsors & Collaborators

• Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders: lead
• Ibrahim Medical College: collaborator

Study Sites (8)

Chapainawabganj Diabetes Center

Chapainawabganj, Bangladesh

RECRUITING

Cox's Bazar Diabetic Hospital

Cox’s Bāzār, Bangladesh

RECRUITING

Meherpur diabetes hospital

Meherpur, Bangladesh

NOT YET RECRUITING

Narayanganj Diabetic Hospital

Nārāyanganj, Bangladesh

RECRUITING

Diabetic Hospital Panchagarh

Panchagarh, Bangladesh

NOT YET RECRUITING

Pirojpur Diabetic Samiti

Pirojpur, Bangladesh

NOT YET RECRUITING

Rajbari Diabetes Center

Rājbāri, Bangladesh

RECRUITING

Sherpur Diabetic Hospital

Sherpur, Bangladesh

NOT YET RECRUITING

Related Publications (4)

• ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, Collins BS, Hilliard ME, Isaacs D, Johnson EL, Kahan S, Khunti K, Leon J, Lyons SK, Perry ML, Prahalad P, Pratley RE, Jeffrie Seley J, Stanton RC, Gabbay RA, on behalf of the American Diabetes Association. 15. Management of Diabetes in Pregnancy: Standards of Care in Diabetes-2023. Diabetes Care. 2023 Jan 1;46(Suppl 1):S254-S266. doi: 10.2337/dc23-S015.

  PMID: 36507645 RESULT

• Islam SMS, Salehin M, Zaman SB, Tansi T, Gupta RD, Barua L, Banik PC, Uddin R. Factors Associated with Chronic Kidney Disease in Patients with Type 2 Diabetes in Bangladesh. Int J Environ Res Public Health. 2021 Nov 23;18(23):12277. doi: 10.3390/ijerph182312277.

  PMID: 34886001 RESULT

• McGrath K, Edi R. Diabetic Kidney Disease: Diagnosis, Treatment, and Prevention. Am Fam Physician. 2019 Jun 15;99(12):751-759.

  PMID: 31194487 RESULT

• Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB, Stein C, Basit A, Chan JCN, Mbanya JC, Pavkov ME, Ramachandaran A, Wild SH, James S, Herman WH, Zhang P, Bommer C, Kuo S, Boyko EJ, Magliano DJ. IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022 Jan;183:109119. doi: 10.1016/j.diabres.2021.109119. Epub 2021 Dec 6.

  PMID: 34879977 RESULT

MeSH Terms

Conditions

Diabetic Nephropathies; Diabetes Mellitus

Condition Hierarchy (Ancestors)

Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Diabetes Complications; Endocrine System Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Wasim MM Haque, MBBS, FCPS

  Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Wasim MM Haque, MBBS, FCPS

CONTACT

+8801915472750; wmmhaque@live.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: May 15, 2024
• First Posted: May 21, 2024
• Study Start: May 11, 2024
• Primary Completion: June 1, 2024
• Study Completion: June 1, 2024
• Last Updated: May 21, 2024

Record last verified: 2024-05

Locations

BA (8)