Dengue Vaccine Hesitancy Among International Travelers

NCT06418854 | Completed

• 1 other identifier: MUTM-2024-030-01
• Study Type: interventional
• Target: 390
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this cross-sectional study is to study dengue vaccine hesitancy among 390 international travelers who visit the Hospital for Tropical Diseases, Bangkok, and three public sites which are the area near the Grand Palace, Khaosan Road, and the snake farm at Queen Saovabha Memorial Institute. The main question it aims to answer is what are the factors associated with the dengue vaccine hesitancy among non-endemic international travelers visiting Thailand. Participants will do the questionnaire consists of three parts

1. 1.Questionnaire to estimate vaccine hesitancy on each 5 domains.
2. 2.Knowledge about dengue infection and vaccination
3. 3.Demographics data of the participants The study prioritizes ethical considerations, confidentiality, and data management to ensure participant welfare and data security.

Conditions

Vaccine Hesitancy

Keywords

Dengue vaccine hesitancy; International travelers; 5C(Confidence, Complacency, Constraints, Risk calculation, Collective responsibility) model

Outcome Measures

Primary Outcomes (1)

• Dengue vaccine hesitancy score

  Spectrum of the dengue vaccine hesitancy score will be assessed by the 15 items questionaire with 7 likert scales adapting from 5C determinants of the vaccine hesitancy. The score ranging from 3-45 for each 5 domains. Higher score will represent stronger impact for each determinants; the positive determinants are confidence and collective responsibility while negative determinants are constraints, complacency, and calculation.

  Baseline

Study Arms (1)

Non-endemic international travelers

EXPERIMENTAL

Other: Questionnaire

Interventions

Questionnaire OTHER

Adapted design questionnaire to estimate the vaccine hesitancy specifically for dengue vaccine

Non-endemic international travelers

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male and female international travelers from dengue-non-endemic countries
• Age ≥18 years old
• Able to read and understand English questionnaire
• Willing to participate in the study Endemic countries of dengue will be defined as all countries in the ASEAN(Association of Southeast Asian Nations) economic community countries, Central and South American countries except Chile, and ten countries in Eastern Mediterranean and Africa showing high frequency of dengue transmission according to WHO(World Health Organization) and ECDC(European Centre for Disease Prevention and Control) data(Yemen, Egypt, Sudan, Eritrea, Djibouti, Tanzania, Kenya, Ethiopia, Somalia, Burkina Faso). Non-endemic countries refer to all the other countries apart from endemic countries.

You may not qualify if:

• Travelers who are visiting the hospital for dengue vaccination or dengue infection or dengue-like symptoms, which is defined as acute fever with one of the following; rash, myalgia, headache, nausea, vomiting, retro-orbital pain.
• Participants who are expatriate workers or lived in Thailand or other Southeast Asia countries for more than 1 year.

Sponsors & Collaborators

• Mahidol University: lead

Study Sites (1)

Hospital for Tropical Diseases

Bangkok, Ratchathewi, 10400, Thailand

Location

MeSH Terms

Conditions

Vaccination Hesitancy

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Vaccination Refusal; Treatment Refusal; Treatment Adherence and Compliance; Health Behavior; Behavior

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc.Prof.

Study Record Dates

• First Submitted: May 8, 2024
• First Posted: May 17, 2024
• Study Start: June 1, 2024
• Primary Completion: November 1, 2024
• Study Completion: December 31, 2024
• Last Updated: February 20, 2025

Record last verified: 2025-01

Locations

TH (1)