The Impact of Colorectal Cancer Screening on Surgical Outcomes

NCT06416501 | Not Yet Recruiting

• 1 other identifier: FudanUcf
• Study Type: observational
• Target: 4,000
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate the pathological characteristics and surgical outcomes of stage III CRC patients detected through screening. Data extracted from the database included the following patient information: age at diagnosis, gender, tumor location, neoadjuvant therapy, surgical procedures, histologic type, differentiation, vascular invasion, perineural invasion, pathological T stage, pathological N stage, and survival outcomes.

Conditions

Prognosis; Colorectal Cancer; Screening

Outcome Measures

Primary Outcomes (1)

• overall survival

  The duration from the initial treatment to either death from any cause or the last recorded follow-up, whichever came first. Assessed up to 100 months.

  the duration from the initial treatment to either death from any cause or the last recorded follow-up, whichever came first. Assessed up to 100 months.

Study Arms (2)

screening

Patients who were detected through any screening test were categorized into the screening group

Other: Mode of detection

nonscreening

Patients who were detected based on symptoms formed the non-screening group.

Interventions

Mode of detection OTHER

Mode of detection

screening

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients who underwent surgical intervention for CRC at Fudan University Shanghai Cancer Center.

You may qualify if:

• Patients who underwent radical surgery for CRC, had confirmed stage III CRC through postoperative pathology, had no prior history of cancer before surgery, and had clear cancer detection information.

Sponsors & Collaborators

• Fudan University: lead

Study Sites (1)

Xinxiang Li

Shanghai, Shanghai Municipality, 200032, China

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor

Study Record Dates

• First Submitted: May 9, 2024
• First Posted: May 16, 2024
• Study Start: May 11, 2024
• Primary Completion: June 1, 2024
• Study Completion: June 15, 2024
• Last Updated: May 16, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will share

Locations

CN (1)