Histologic Comparison of Ablative Techniques for Endometriosis
1 other identifier
interventional
141
1 country
1
Brief Summary
To our knowledge, no other human studies directly compare the effectiveness of the various ablative technologies. We set out to design a study to directly compare ablative energy sources and evaluate their ability to destroy native endometriosis tissue in humans.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started May 2024
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 9, 2024
CompletedFirst Submitted
Initial submission to the registry
May 10, 2024
CompletedFirst Posted
Study publicly available on registry
May 16, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 9, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 9, 2025
CompletedMay 30, 2024
May 1, 2024
1 year
May 10, 2024
May 28, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Positive Histology
Endometriosis seen on pathologic sample.
0 days
Secondary Outcomes (1)
Pelvic Pain
3 months
Study Arms (3)
Diathermy
ACTIVE COMPARATORCO2 Laser
ACTIVE COMPARATORArgon Beam Coagulator
ACTIVE COMPARATORInterventions
Argon Beam Coagulator will be used to ablate the randomized sample.
Eligibility Criteria
You may qualify if:
- Adult women 18 years of age or older
- Already planning to undergo scheduled robotic assisted or laparoscopic excision of lesions for pelvic pain symptoms (pelvic pain, dysmenorrhea, dyspareunia, dysuria, dyschezia, ovarian pain) or endometriosis of any kind (endometriosis of any location, or endometrioma)
You may not qualify if:
- Known pregnancy at enrollment or at the time of the excision surgery
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- TriHealth Inc.lead
Study Sites (1)
Good Samaritan Hospital
Cincinnati, Ohio, 45220, United States
Related Publications (1)
Namaky DD, Carrel-Lammert M, Hoehn J, Yeung J. Histologic Comparison of Ablative Techniques for Endometriosis: a Randomized Trial. J Minim Invasive Gynecol. 2026 Jan 10:S1553-4650(26)00044-0. doi: 10.1016/j.jmig.2026.01.020. Online ahead of print.
PMID: 41525928DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Masking Details
- Pathologist is blinded to treatment arm
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 10, 2024
First Posted
May 16, 2024
Study Start
May 9, 2024
Primary Completion
May 9, 2025
Study Completion
June 9, 2025
Last Updated
May 30, 2024
Record last verified: 2024-05
Data Sharing
- IPD Sharing
- Will not share