Clinical Effectiveness of Boxing Training in Individuals With Elevated Blood Pressure or Stage 1 Hypertension

NCT06413251 | Completed

• 1 other identifier: 1364179-3
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to determine whether boxing training reduces cardiovascular risk in elevated blood pressure or hypertension stage 1 individuals. The main questions it aims to answer are (1) if boxing training reduces peripheral and central blood pressure and (2) if boxing training improves cardiovascular function in elevated blood pressure or hypertension stage 1 individuals. Participants with elevated blood pressure or hypertension stage 1 will be randomly divided into a control group or an intervention group. The latter group will be involved in boxing training, 3 days per week for 6 weeks. Researchers will compare clinical and cardiovascular outcomes between the control and the intervention group.

Conditions

Elevated Blood Pressure; Hypertension

Outcome Measures

Primary Outcomes (1)

• Change from baseline brachial blood pressure after week six

  Resting systolic and diastolic blood pressure (mmHg)

  pre-intervention and immediately after the intervention

Secondary Outcomes (18)

• Central Blood Pressure

  pre-intervention and immediately after the intervention

• Vascular function

  pre-intervention and immediately after the intervention

• Plethysmography

  pre-intervention and immediately after the intervention

• Maximum Oxygen Uptake

  pre-intervention and immediately after the intervention

• Nitric Oxide Bioavailability

  pre-intervention and immediately after the intervention

Study Arms (2)

Boxing

EXPERIMENTAL

The boxing training intervention will consist of three exercise sessions per week on nonconsecutive days for six weeks

Other: Boxing Training

Control

PLACEBO COMPARATOR

The control group will perform three days per week 10 minutes a flexibility intervention.

Other: Control flexibility

Interventions

Boxing Training OTHER

The boxing training intervention will consist of three exercise sessions per week on nonconsecutive days for six weeks. Participants will be instructed to complete 10 rounds of three minutes with a one-minute resting period interspersed. Four rounds will consist of heavy bag punching (e.g. straight, jab, hook) at 60% VO2max and three rounds at 90-95% VO2max, while the remaining 3 rounds will be focused on mitt work at 60% VO2max.

Also known as: Exercise

Boxing

Control flexibility OTHER

The control group will perform three days per week 10 minutes of dynamic articular movement, five minutes of uni pedal stance, and five minutes of stretching of the upper limbs for six weeks.

Control

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ≥18 years old.
• Systolic blood pressure between 120-139 mmHg and/or diastolic blood pressure between 80-89 mmHg obtained from 2 different days.
• an estimated 10-year risk of CVD ≤10%, calculated by the ACC/AHA Pooled Cohort Equations.
• no current participation in 3 or more days per week of endurance or resistance exercise training.

You may not qualify if:

• non-controlled cardiac, pulmonary, or metabolic diseases.
• smoking, consumption of nutritional supplements containing antioxidants.
• any physical impairment to exercise.

Sponsors & Collaborators

• University of Texas, El Paso: lead

Study Sites (1)

The University of Texas at El Paso

El Paso, Texas, 79968, United States

Location

MeSH Terms

Conditions

Hypertension

Interventions

Exercise

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants will be recruited from the University of Texas at El Paso and its surroundings. They will be identified by a preliminary blood pressure screening and a health questionnaire. The inclusion criteria will consist on: (1) ≥18 years old, (2) SBP between 120-139 mmHg or DBP between 80-89 mmHg obtained from 2 different days, (3) an estimated 10-year risk of CVD ≤10%, calculated by the ACC/AHA Pooled Cohort Equations, and (4) no current participation in 3 or more days per week of endurance or resistance exercise training. Exclusion criteria will include non-controlled cardiac, pulmonary, or metabolic diseases, smoking, consumption of nutritional supplements containing antioxidants, and any physical impairment to exercise.

Study Record Dates

• First Submitted: November 22, 2023
• First Posted: May 14, 2024
• Study Start: January 15, 2020
• Primary Completion: March 15, 2020
• Study Completion: March 15, 2020
• Last Updated: May 14, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)