Peer-led Digital Health Lifestyle Intervention for a Low Income Community at Risk for Cardiovascular Diseases (MYCardio-PEER)

NCT06408493 | Completed

• 1 other identifier: 36440
• Study Type: interventional
• Target: 63
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this interventional study is to develop and assess the effectiveness of a peer-led digital health program (MYCardio-PEER) for primary prevention of cardiovascular disease (CVD) in a low-income community at-risk of CVD. The main questions it aims to answer are:

• Is MYCardio-PEER effective in improving knowledge, lifestyle behaviors and CVD biomarkers of a low-income community at-risk for CVD?
• Is there an association between MYCardio-PEER participants' adherence and satisfaction, with effectiveness and sustainability of the program? Participants will attend the 8-weeks MYCardio-PEER program with their peer leaders, supplemented with face-to-face components. Participants will then be followed up for another 12 weeks, during which peer leaders and researchers will have minimal contact with the participants. Participants who have been allocated into the control group will receive printed documents with standard tips on dietary and lifestyle management for CVD, where they will be encouraged to maintain regular calorie intake and expenditure and perform regular exercise.

Conditions

Primary Prevention of Cardiovascular Diseases

Keywords

Peer-led; Primary prevention; Cardiovascular diseases; Digital health; Lifestyle intervention; Peer support; Community

Outcome Measures

Primary Outcomes (1)

• Framingham Risk Score for Cardiovascular Disease Risk

  The score is based on a person's age, sex, blood pressure, cholesterol levels, smoking status, and diabetes status. The calculated score will be converted into 10-year risk percentage whereby the higher the percentage means higher cardiovascular disease risk.

  20 weeks

Secondary Outcomes (18)

• Blood pressure

  20 weeks

• Total cholesterol level

  20 weeks

• High-density lipoprotein cholesterol (HDL-C) level

  20 weeks

• Low-density lipoprotein cholesterol (LDL-C) level

  20 weeks

• Triglycerides level

  20 weeks

Study Arms (2)

Intervention

EXPERIMENTAL

Participants will attend the 8-weeks MYCardio-PEER program with their peer leaders, supplemented with face-to-face components.

Behavioral: MYCardio-PEER

Control

NO INTERVENTION

Participants will receive printed documents with standard tips on dietary and lifestyle management for CVD.

Interventions

MYCardio-PEER BEHAVIORAL

MYCardio-PEER participants will attend an 8-weeks intervention program delivered over the social networking application. Bite-sized videos and infographic posters on healthy diet and lifestyle for primary prevention of CVD will be delivered weekly, supplemented by interactive peer-group activities to encourage behavior change.

Intervention

Eligibility Criteria

• Age: 30 Years - 74 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Mentally sound man/woman of at least 30 years old
• Monthly household income of less than RM3,710 or receiving government aid for low-income community
• Literate with a fair command of the Malay language
• Have mobile device connected to the Internet
• Willing to attend 8 weeks of intervention and be followed up for another 12 weeks during the maintenance phase.
• Have been confirmed to have a moderate or high risk for CVD based on the Framingham General CVD Risk Score

You may not qualify if:

• Pregnant, lactating or intend to become pregnant during the study period.
• Any other pre-existing conditions or severe complications that could compromise the ability to adhere to the study program.
• Enrolled in other studies.

Sponsors & Collaborators

• Monash University Malaysia: lead
• Ministry of Higher Education, Malaysia: collaborator

Study Sites (1)

Monash University

Subang Jaya, Selangor, 47500, Malaysia

Location

Related Publications (2)

• Lim GP, Appalasamy JR, Ahmad B, Quek KF, Ramadas A. Peer-Led Digital Health Lifestyle Intervention in a Low-Income Community at Risk for Cardiovascular Disease (MYCardio-PEER): Mixed Methods Development and Process Evaluation Study. J Med Internet Res. 2025 Nov 12;27:e77063. doi: 10.2196/77063.

  PMID: 41222971 DERIVED

• Lim GP, Appalasamy JR, Ahmad B, Quek KF, Shaharuddin S, Ramadas A. Peer-led digital health lifestyle intervention for a low-income community at risk for cardiovascular diseases (MYCardio-PEER): a quasi-experimental study protocol. Prim Health Care Res Dev. 2025 Mar 3;26:e20. doi: 10.1017/S1463423625000192.

  PMID: 40025749 DERIVED

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

• Amutha Ramadas, PhD

  Monash University Malaysia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 18, 2024
• First Posted: May 10, 2024
• Study Start: March 1, 2024
• Primary Completion: October 30, 2024
• Study Completion: December 31, 2024
• Last Updated: December 5, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

MY (1)