NCT06405919

Brief Summary

To determine the incidence of thyroid cancer in patients with long standing goitres presenting for surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2017

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2018

Completed
5.6 years until next milestone

First Submitted

Initial submission to the registry

May 4, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 9, 2024

Completed
Last Updated

May 9, 2024

Status Verified

May 1, 2024

Enrollment Period

1.6 years

First QC Date

May 4, 2024

Last Update Submit

May 4, 2024

Conditions

Incidence of Thyroid Cancer in Long Standing MNG

Keywords

: goitre, long standing, malignant risk, incidental.

Outcome Measures

Primary Outcomes (1)

  • Rate of malignancy

    Rate of malignancy in resected goitre specimens

    March 2017-September 2018

Study Arms (1)

Patients with goitres 10 years or more

Patients with long standing multinodular goitres of 10years or more presenting to surgical unit in Khartoum Teaching Hospital -Sudan. Checking incidence of malignancy in this group.

Diagnostic Test: Histopathology

Interventions

HistopathologyDIAGNOSTIC_TEST

Thyroidectomy for patients and histological examination of specimen to determine incidence of malignancy.

Patients with goitres 10 years or more

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with long standing goitres presenting for surgery in Khartoum Teaching Hospital March 2017-September 2018

You may qualify if:

  • All patients with long standing goitres of 10 years or more

You may not qualify if:

  • Non

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Medicine University of Khartoum

Khartoum, 11111, Sudan

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Resected goitres for histopathology

MeSH Terms

Conditions

Goiter

Condition Hierarchy (Ancestors)

Thyroid DiseasesEndocrine System Diseases

Study Officials

  • Mohamed Elmakki Abdella, MS,FRCSI

    University of Khartoum -Faculty of Medicine

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate professor of surgery

Study Record Dates

First Submitted

May 4, 2024

First Posted

May 9, 2024

Study Start

March 1, 2017

Primary Completion

September 30, 2018

Study Completion

September 30, 2018

Last Updated

May 9, 2024

Record last verified: 2024-05

Locations

SU(1)