ARISCAT, ASA and LAS VEGAS Risk Scores and the Incidence of Postoperative Pulmonary Complications in Thoracic Surgery

NCT06404892 | Recruiting

• 1 other identifier: 75871723.4.0000.5530
• Study Type: observational
• Target: 110
• Locations: 1 country
• Sites: 1

Brief Summary

Postoperative pulmonary complications (PPC) are among the main complications after the anesthetic-surgical procedure. It can be said that thoracic surgery results in impaired respiratory function in the postoperatively, due to the decrease in lung volumes and capacities (the vital capacity decreases by approximately 50-60% and functional residual capacity decreases by approximately 30% in the first 24 hours after surgery) diaphragm dysfunction, gas exchange impaired, cough and ineffective mucociliary clearance. Thus, our hypothesis is that the application of preoperative risk scores normally used for non-cardiac and non-thoracic surgeries may be effective on the predictability of the occurrence of CPP in patients undergoing ventilation single-lung. This is a prospective observational study in order to evaluate the performance of the ASA, ARISCAT and LAS VEGAS risk scores for predict the occurrence of postoperative pulmonary complications (PPC) in patients undergoing thoracic surgery with single-lung ventilation.

Conditions

Postoperative Complications

Keywords

postoperative pumonary complications; ARISCAT score; LAS VEGAS score; ASA score

Outcome Measures

Primary Outcomes (1)

• Postoperative pulmonary complications

  Incidence of composite pulmonary complications after surgery

  up to 30 days after surgery

Study Arms (1)

Group 1

Patients undergoing thoracic surgery and single-lung ventilation.

Procedure: Single-lung ventilation

Interventions

Single-lung ventilation PROCEDURE

Patients undergoing thoracic surgery and intraoperative single-lung ventilation.

Group 1

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adult patients undergoing any thoracic procedure associated with intraoperative use of single-lung ventilation.

You may qualify if:

• Adult patients undergoing any thoracic procedure associated with intraoperative single-lung ventilation.

You may not qualify if:

• Patients undergoing cardiac surgery, pregnant women, patient refusal, contraindications to proposed surgical, anesthetic or analgesic techniques, sepsis, psychiatric illness, uncontrolled endocrine, kidney or liver disease and coagulopathies.

Sponsors & Collaborators

• Hospital Nossa Senhora da Conceicao: lead

Study Sites (1)

HCPA

Porto Alegre, Rio Grande do Sul, 90035903, Brazil

RECRUITING

MeSH Terms

Conditions

Postoperative Complications

Interventions

One-Lung Ventilation

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Respiration, Artificial; Airway Management; Therapeutics

Study Officials

• Andre P Schmidt, MD

  Hospital Nossa Senhora da Conceição

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Andre P Schmidt, MD

CONTACT

5551996412212; aschmidt@ghc.com.br

Rejane Piantamar

CONTACT

555133572419; prejane@ghc.com.br

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiologist

Study Record Dates

• First Submitted: May 5, 2024
• First Posted: May 8, 2024
• Study Start: July 1, 2024
• Primary Completion: December 1, 2025
• Study Completion: December 31, 2025
• Last Updated: May 6, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)