The Benefits of R Anastomotic Technique for Billroth-II Reconstruction With Braun Anastomosis During Totally Laparoscopic Distal Gastrectomy: a Propensity Score Matching Analysis

NCT06404580 | Completed

• 1 other identifier: R vs B-II-B
• Study Type: observational
• Target: 246
• Locations: 1 country
• Sites: 1

Brief Summary

Between March 2019 and September 2022 in our centre, R anastomosis was performed on 123 patients undergoing TLDG for distal gastric cancer. A retrospective review of a prospectively collected database identified patients who underwent TLDG between January 2010 and September 2022. Patients who underwent R anastomosis were matched in a 1:1 ratio with patients who underwent conventional anastomosis using a propensity score based on age, sex, preoperative BMI, American Society of Anesthesiologists (ASA) score, and the history of abdominal surgery. Surgical and postoperative outcomes and clinicopathological data were analyzed for both groups.

Conditions

the Incidences of Clavien-Dindo Grade II or Higher; Anastomotic Time

Outcome Measures

Primary Outcomes (2)

• the incidences of Clavien-Dindo grade II or higher

  the incidences of Clavien-Dindo grade II or higher

  2010-2022

• anastomotic time

  anastomotic time

  2010-2022

Study Arms (2)

R anastomosis

Procedure: R anastomosis

B-II-B anastomosis

Procedure: R anastomosis

Interventions

R anastomosis PROCEDURE

R anastomosis

B-II-B anastomosis; R anastomosis

Eligibility Criteria

• Age: 35 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

between March 2019 and September 2022 at Northern Jiangsu people's hospital were prospectively collected, and data from patients who underwent conventional anastomosis (control group) were retrospectively collected from the same prospectively maintained database of patients who underwent TLDG between January 2010 and February 2019 at Northern Jiangsu people's hospital.

You may qualify if:

• elective surgery for endoscopic and pathological diagnosis of malignant tumour of the gastric antrum or body with no distant metastases confirmed by multilayer spiral computed tomography;
• patients who underwent B-II-B anastomosis during TLDG; and (3) patients who could be followed up postoperatively.

You may not qualify if:

• (1) patients who had received preoperative neoadjuvant radiotherapy or chemotherapy; (2) patients undergoing emergency surgery; (3) the presence of other malignant tumours concurrently; and (4) patients who were lost to follow-up.

Sponsors & Collaborators

• Daorong Wang: lead

Study Sites (1)

Northern Jiangsu People's Hospital

Yangzhou, Jiangsu, 225001, China

Location

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: DR

Study Record Dates

• First Submitted: May 5, 2024
• First Posted: May 8, 2024
• Study Start: March 1, 2019
• Primary Completion: September 1, 2022
• Study Completion: January 1, 2023
• Last Updated: May 8, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)