A Training Program of Drug Allergy for Healthcare Professionals

NCT06399601 | Not Yet Recruiting

• 1 other identifier: Drugallergy
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Drug allergy is often under-recognized, yet over- (mistakenly) diagnosed, especially in Hong Kong. There is also a dire shortage of allergy specialists and facilities to tackle the overwhelming drug allergy pandemic. Fortunately, when trained, non-specialist physicians and nurses have demonstrated comparable capabilities in drug allergy evaluation compared to specialists. To potentially promote and propagate the role of non-specialist physicians and nurses toward drug allergy care, the investigators propose a study to investigate the impact of an intensive and focused drug allergy educational course conducted at the University of Hong Kong.

Conditions

Drug Allergy

Keywords

Drug allergy

Outcome Measures

Primary Outcomes (1)

• Change in knowledge of drug allergy as measured by the validated drug allergy questionnaire

  Knowledge includes mechanism, clinical manifestations, diagnosis and management of drug allergy. A binary variable scale were used to ascertain level of the knowledge (from 0 to 1: 0, wrong; 1, right). Answers formats consisted of 4-choice questions (total 14 questions).

  After the 2-day training course

Study Arms (2)

Intervention group

EXPERIMENTAL

wo identical didactic courses on drug allergy will be delivered. Changes in knowledge and clinical practice will be measured by serial practice questionnaires and knowledge quizzes conducted before and after the course. Group 1 will undergo the course first.

Other: Drug allergy training program

Control group

ACTIVE COMPARATOR

Group 2 will undergo an identical course one month later. By comparing any changes in knowledge or practice between groups, this ensures that any changes in knowledge or practice were solely due to the course and not other external factors.

Other: Drug allergy training program

Interventions

Drug allergy training program OTHER

Two identical didactic courses on drug allergy were designed. Each course will last 12 hours and conducted over 2 consecutive days (6 hours each day). All candidates will attend physically and on-site. Various aspects of drug allergy with pre-set learning objectives will be taught in-person by instructors (physicians or nurses specializing in drug allergy nominated by the University of Hong Kong). Course materials and instructors will be identical for each course.

Control group; Intervention group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Registered nurses or doctors actively practicing in Hong Kong
• English speaking;
• Able to complete quizzes and questionnaires;
• Aged 18 or above

You may not qualify if:

• People who are unable to communicate in Cantonese or Mandarin
• People who are participating in other drug allergy training course

Sponsors & Collaborators

• The University of Hong Kong: lead

Study Sites (1)

School of Biomedical Science

Hong Kong, 000, Hong Kong

Location

Related Publications (1)

• Mak HWF, Meng J, Chung FKL, Lee JTY, Aberathna IS, Amarasekara U, Ranasinghe TND, Jayamali J, Yang Q, Zhou M, Chen L, Huang JX, Shi W, Kulkarni R, Peter JG, Trubiano JA, Jeewandara KC, Lucas M, Li PH. Bridging Global Disparities in Drug Allergy Through AI-Assisted Training for Non-Specialists: Findings From the Multinational ADAPT-2 Course. Clin Exp Allergy. 2026 Jan 20. doi: 10.1111/cea.70213. Online ahead of print.

  PMID: 41558734 DERIVED

MeSH Terms

Conditions

Drug Hypersensitivity

Condition Hierarchy (Ancestors)

Drug-Related Side Effects and Adverse Reactions; Chemically-Induced Disorders

Central Study Contacts

Hei Li, MBBS

CONTACT

2255 5995; liphilip@hku.hk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 9, 2024
• First Posted: May 6, 2024
• Study Start: December 9, 2024
• Primary Completion: December 16, 2024
• Study Completion: December 16, 2024
• Last Updated: May 6, 2024

Record last verified: 2024-04

Locations

HK (1)