Exercise-induced Hypoalgesia in Patients With Knee Osteoarthritis
1 other identifier
interventional
40
0 countries
N/A
Brief Summary
The main objective of this study is to evaluate the differences in the phenomenon of exercise-induced hypoalgesia in patients with osteoarthritis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable knee-osteoarthritis
Started May 2024
Shorter than P25 for not_applicable knee-osteoarthritis
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 23, 2024
CompletedFirst Posted
Study publicly available on registry
May 3, 2024
CompletedStudy Start
First participant enrolled
May 15, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 15, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 15, 2024
CompletedMay 3, 2024
April 1, 2024
5 months
April 23, 2024
April 30, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Algometry
Pressure pain thresholds will be measured at the affected knee, the contralateral knee and the contralateral epicondyle.
Before and after exercise (1 month)
Study Arms (1)
Exercise
EXPERIMENTALInterventions
Participants will perform 8 sessions of 4 sets of knee extension exercises during 1 month
Eligibility Criteria
You may qualify if:
- diagnosed with severe knee OA (according to the clinical and radiographic criteria of the American College of Rheumatology Guidelines)
You may not qualify if:
- pain in the contralateral (non-studied) limb (maximum ≥80 of 100 mm on a visual analog scale (VAS) during daily activities),
- undergone another hip or knee joint replacement in the previous year
- any medical condition in which exercise was contraindicated
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD
Study Record Dates
First Submitted
April 23, 2024
First Posted
May 3, 2024
Study Start
May 15, 2024
Primary Completion
October 15, 2024
Study Completion
December 15, 2024
Last Updated
May 3, 2024
Record last verified: 2024-04