Evaluation of Accelerated Sampling Techniques for Vessel Wall Imaging
Optimizing Scan Efficiency of T1-weighted (T1w) Imaging for Vessel Wall Imaging Protocols
1 other identifier
observational
15
1 country
2
Brief Summary
The purpose of this study is to compare and evaluate a faster MR image that has been optimized to look at participants blood vessel walls.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Aug 2027
Typical duration for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 25, 2024
CompletedFirst Posted
Study publicly available on registry
April 30, 2024
CompletedStudy Start
First participant enrolled
August 1, 2027
ExpectedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2029
Study Completion
Last participant's last visit for all outcomes
July 1, 2030
September 8, 2025
September 1, 2025
1.8 years
April 25, 2024
September 5, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Optimizing scan efficiency of T1-weighted (T1w) imaging for vessel wall imaging protocols
The primary outcome of the study will be the raters study where qualitative imaging scores will be provided by experienced radiologists using a four-point scale.
24 months
Eligibility Criteria
The staff will be observant of issues related to undue influence as it relates to any vulnerable populations in the event, they are eligible and enrolled in the study (e.g. there will be no impact on grades, employment status, access to medical care or information). If employees, students, etc. meet the eligibility criteria and are enrolled we will do a thorough and sensitive informed consent process in order to protect their rights and minimize any risk of coercion or undue influence.
You may qualify if:
- \. Patients 18 years of age and scheduled to undergo clinical vessel wall MR imaging exams as part of their standard of care.
You may not qualify if:
- Any person under the age of 18
- Presence of artifact-producing intracranial devices (aneurysm clips/coils, ventricular drains, craniectomy mesh, etc.)
- Any person with contraindications to MRI (medical instability, non-MRI compatible implanted devices, retained metallic foreign bodies, claustrophobia)
- Large space-occupying lesions (50 mL) or substantial mass effect (herniation, 5mm midline shift) on preceding brain imaging,
- Imminently life-threatening co-morbid conditions
- A history of premorbid disabling neurological or psychiatric disease, current substance abuse or remote substance abuse with permanent organic sequelae
- Pregnancy or lactation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
University of Pennsylvania Hospital
Philadelphia, Pennsylvania, 19104, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 25, 2024
First Posted
April 30, 2024
Study Start (Estimated)
August 1, 2027
Primary Completion (Estimated)
June 1, 2029
Study Completion (Estimated)
July 1, 2030
Last Updated
September 8, 2025
Record last verified: 2025-09
Data Sharing
- IPD Sharing
- Will not share