The Role of High Intraoperative Fraction of Inspired Oxygen in Preventing Postoperative Nausea and Vomiting

NCT06390280 | Completed

• 1 other identifier: E2-22-2167
• Study Type: observational
• Target: 98
• Locations: 1 country
• Sites: 1

Brief Summary

Postoperative nausea and vomiting is one of the most common complications after laparoscopic surgeries. The investigators aimed to evaluate the effects of intraoperative high fraction of inspired oxygen in preventing postoperative nausea and vomiting according to Apfel score in laparoscopic cholecystectomy patients.

Conditions

Postoperative Nausea and Vomiting; Laparoscopic Cholecystectomy

Outcome Measures

Primary Outcomes (2)

• Postoperative nausea and vomiting

  the investigators aimed to compare postoperative nause and vomiting

  at the postoperative 15.minutes

• Postoperative nausea and vomiting 24.hours

  the investigators aimed to compare postoperative nause and vomiting

  at the postoperative 24.hours

Secondary Outcomes (2)

• Postoperative antiemetic 15. minutes

  at the postoperative 15.minutes

• Postoperative antiemetic 24.hours

  at the postoperative 24.hours

Study Arms (2)

grup I

Intraoperative Fraction of Inspired Oxygen %30 applied

Procedure: intraoperative Fraction of Inspired Oxygen

grup II

Intraoperative Fraction of Inspired Oxygen %80 applied

Procedure: intraoperative Fraction of Inspired Oxygen

Interventions

intraoperative Fraction of Inspired Oxygen PROCEDURE

Group I intraoperative Fraction of Inspired Oxygen 30%, Group II intraoperative Fraction of Inspired Oxygen 80% applied group.

grup I; grup II

Eligibility Criteria

• Age: Up to 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

A total of 98 patients, under the age of 60, in the ASA I-II risk group, who underwent laparoscopic cholecystectomy surgery were included.

You may qualify if:

• Patients undergoing elective laparoscopy cholecystectomy surgery
• Patients younger than 60 years old
• Both genders
• American Society of Anesthesiologists (ASA) I-II risk group

You may not qualify if:

• pregnancy, patients who do not want to participate in the study, surgery time \> 2 hours

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara Bilkent City Hospital

Ankara, Bilkent, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Postoperative Nausea and Vomiting

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Nausea; Signs and Symptoms, Digestive; Signs and Symptoms; Vomiting

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 14, 2023
• First Posted: April 30, 2024
• Study Start: July 10, 2022
• Primary Completion: January 30, 2023
• Study Completion: February 28, 2023
• Last Updated: April 30, 2024

Record last verified: 2024-04

Locations

TU (1)