STAMPS: South Carolina Buprenorphine Treatment Initiation, Adherence, and Retention Utilizing Mobile Health Units and Peer Support Specialists

NCT06384781 | Completed DMC

• 2 other identifiers: 2130836R61DA059892-01
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 2

Brief Summary

The study is a 1-arm prospective interventional cohort quasi-experimental with retrospective control group. Enrolled participants will be compared to previously established mobile health patients, who did not work with a peer recovery coach, for buprenorphine treatment and adherence outcomes. 90 patients will be recruited from the mobile health units in rural counties in Upstate South Carolina. Visits consist of a baseline and 3 month follow up. The study will focus to develop, deliver, and evaluate an innovative 1) Peer Support Specialist (PSS) intervention to increase Medications for Opioid Use Disorder (MOUD) initiation and retention rates in rural populations and underserved communities, and 2) dynamic modeling framework to prioritize at-risk communities for delivery of Mobile Health Clinics. the interventions will be developed in the R61 phase and implemented in a pilot study to determine the effectiveness on initiation and retention. With opioid overdose deaths continuing to rise in South Carolina (SC) and nationally, our sustainable framework has potential to prevent hundreds to thousands of opioid overdoses in SC and can be scaled up in other regions to save many more lives.

Conditions

Opioid Use Disorder

Keywords

peer support specialist; peer recovery coach; OUD; opioid use disorder; mobile health clinic; rural

Outcome Measures

Primary Outcomes (2)

• Medication for Opioid Use Disorder (MOUD) Initiation

  MOUD initiation is defined as receipt of first MOUD prescription within the 3-month study period

  3 months

• MOUD Retention

  MOUD retention is defined as receipt of 75% of weekly MOUD prescriptions in first 3 months since MOUD initiation

  3 months

Study Arms (1)

Peer Support Specialist Intervention

EXPERIMENTAL

Eligible participants will be linked to a peer support specialist. Peer support specialists are Certified Peer Support Specialists (CPSS) who have lived experience with opioid use disorder (OUD) and OUD recovery. Peer support specialists offer consistent personalized recovery support and generalized social support. Peer support specialists will maintain contact and provide support for the participant for 3 months post-baseline utilizing the newly validated checklist.

Behavioral: Peer Support Checklist

Interventions

Peer Support Checklist BEHAVIORAL

Peer support specialists are Certified Peer Support Specialists (CPSS) who have lived experience with Opioid Use Disorder (OUD) and OUD recovery. Peer support specialists offer consistent personalized recovery support and generalized social support. Peer support specialists will maintain contact and provide support for the participant for six-months post-baseline. CPSS will utilize the newly developed checklist from earlier phases of the project to provide patient support.

Peer Support Specialist Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18+
• Have diagnosis of OUD
• New patient of the mobile clinic

You may not qualify if:

• Currently prescribed MOUD
• Currently working with a PSS
• Current suicidal ideation, as verified through the Patient Health Questionnaire-9 (PHQ-9)
• Having a severe medical or psychiatric disability that would hinder participation in the study, as determined by nurse practitioner
• Unable to read/speak English
• Unable to read and comprehend the consent materials and other study materials

Sponsors & Collaborators

• Prisma Health-Upstate: lead
• Clemson University: collaborator
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (2)

Prisma Addiction Medicine Center - Mobile Health Clinic

Clinton, South Carolina, 29325, United States

Location

Prisma - Addiction Medicine Center Mobile Health Clinic

Seneca, South Carolina, 29672, United States

Location

Related Links

• NIH RePORTER

MeSH Terms

Conditions

Opioid-Related Disorders

Condition Hierarchy (Ancestors)

Narcotic-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 22, 2024
• First Posted: April 25, 2024
• Study Start: May 2, 2024
• Primary Completion: July 31, 2025
• Study Completion: July 31, 2025
• Last Updated: October 23, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (2)