Trials Sponsors Conditions Drugs Pricing

Conditions

Necrotizing Pancreatitis

Keywords

Acute Necrotizing Pancreatitissepsisorgan dysfunction

Outcome Measures

Primary Outcomes (1)

Measure organ dysfunction change after open necrosectomy with respect to time
Organ dysfunction will be measured using sequential organ failure assessment score scale. The scores range from 0 (normal) to 4(most abnormal) for each organ, with higher scores indicating worse health status
up to postoperative day 7, or at hospital discharge, whichever comes first

Secondary Outcomes (11)

incidence of a composite of major complications
up to postoperative day 28
Incidence of ICU mortality
through study completion, an average of 1year
Incidence of hospital mortality
through study completion, an average of 1 year
Incidence of 28-day mortality
through study completion, an average of 1 year
Incidence of one year mortality
through study completion, an average of 1 year
+6 more secondary outcomes

Study Arms (1)

Pancreatitis with sepsis patients' organ dysfunction progression after open necrosectomy

Acute necrotizing pancreatitis patients with sepsis undergoing open necrosectomy will be measured SOFA scores at a special time point to characterize organ dysfunction experience profiles.

Other: Necrotizing Pancreatitis patients' organ dysfunction progression

Interventions

Necrotizing Pancreatitis patients' organ dysfunction progressionOther

Study the dynamic nature of organ dysfunction

Pancreatitis with sepsis patients' organ dysfunction progression after open necrosectomy

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

Acute necrotizing pancreatitis Patients with sepsis scheduled for open necrosectomy will be invited to participate in this study.

You may qualify if:

Patients 18 years or older

Sponsors & Collaborators

Chunling Jiang
Otherlead

Study Sites (1)

West China Hospital, Sichuan University

Chengdu, China, 610041, China

RECRUITING

Fengming Luo, PhDCONTACT02885423593 jiangchunling@scu.edu.cn

MeSH Terms

Conditions

Pancreatitis, Acute NecrotizingSepsis

Condition Hierarchy (Ancestors)

PancreatitisPancreatic DiseasesDigestive System DiseasesInfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

Fengming Luo, PhD
West China Hospital
PRINCIPAL INVESTIGATOR

Central Study Contacts

Chunling Jiang, PhD

CONTACT

18980601096 jiangchunling@scu.edu.cn

Qian Li, PhD

CONTACT

18980601096

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Professor

Study Record Dates

First Submitted

March 26, 2024

First Posted

April 24, 2024

Study Start

June 15, 2024

Actual (reported)

Primary Completion

December 30, 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (11)

Study Arms (1)

Pancreatitis with sepsis patients' organ dysfunction progression after open necrosectomy

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (11)

Study Arms (1)

Pancreatitis with sepsis patients' organ dysfunction progression after open necrosectomy

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations