Myoelectric Activity and Mandibular Movement for the Diagnosis of Temporomandibular Disorder

NCT06372769 | Completed

• 1 other identifier: 20240304
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to provide normal reference values of surface electromyography (sEMG) and mandibular kinematics in Chinese young adults, compare the sex differences and assess the diagnosis value of these indices.

Conditions

Temporomandibular Disorder

Keywords

Temporomandibular joint disorder;; Surface electromyography;; Mandibular kinematics;; Sex difference;; Diagnosis.

Outcome Measures

Primary Outcomes (1)

• Surface electromyography (μV)

  The sEMG of the anterior temporalis (TA), masseter (MM), sternocleidomastoid (cervical group, CG), and digastric (DA) during mandibular postural position and maximal clench were recorded.

  3 days

Secondary Outcomes (1)

• Mandibular kinematics (mm, mm/s)

  3 days

Study Arms (2)

Healthy young adults with individual normal occlusion

Healthy subjects who fulfilled the following criteria: centred midline and no marked restriction and deviation of mouth opening and closing; overjet and overbite of 1-3 mm, bilateral molar support with molar and cusp relation of Angle's class I, and presence of complete permanent dentition, except third molars.

Diagnostic Test: electromyograph and kinesiograph

Temporomandibular disorder patients with disc displacement

Patients with unilateral or bilateral temporomandibular joint (TMJ) disc displacement symptoms, such as TMJ clicking, TMJ locking, and limitation in opening mouth were included in the study. The study did not cover the patients with muscle disorders (myofascial pain), with arthralgia, osteoarthritis, and osteoarthrosis, with TMJ fracture, with dentofacial deformity, with systemic disease affecting TMJ, and undergone TMD treatments.

Diagnostic Test: electromyograph and kinesiograph

Interventions

electromyograph and kinesiograph DIAGNOSTIC_TEST

The sEMG of the anterior temporalis (TA), masseter (MM), sternocleidomastoid (cervical group, CG), and digastric (DA) were recorded simultaneously with an sEMG device (K7/EMG, USA) using disposable silver/silver chloride bipolar surface electrodes. First, sEMG was conducted on four pairs of muscles (TA, MM, CG, and DA) in the MPP, and subjects were guided to maintain the face and jaw as relaxed as possible. To determine the relative efficiency of muscle function, the second test was performed to measure the sEMG of TA and MM during the maximal biting force against natural dentition. In the third test, subjects were guided to clench three times to monitor early motor unit recruitment as they closed from rest through freeway space to initial tooth contact. Kinesiographic recordings were performed using a kinesiograph (K7/Computerized Mandibular Scanning (CMS), USA) that measured the maximum mouth opening (MMO) and opening and closing velocities.

Healthy young adults with individual normal occlusion; Temporomandibular disorder patients with disc displacement

Eligibility Criteria

• Age: 20 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Healthy volunteers were recruited from college students of Fujian Medical University, while the temporomandibular disorder participants were recruited through public invitations, via recruitment posters and personal contacts.

You may qualify if:

• Centred midline and no marked restriction and deviation of mouth opening and closing; ·Overjet and overbite of 1-3 mm, bilateral molar support with molar and cusp relation of Angle's class I;
• Presence of complete permanent dentition, except third molars.

You may not qualify if:

• History of local or general trauma;
• Presence of systemic diseases, neurological or psychiatric disorders, muscular diseases, cervical pain, or TMD based on the Research Diagnostic Criteria (RDC);
• Pregnancy;
• Consumption of anti-inflammatory, analgesic, antidepressant, or myorelaxant drugs;
• Presence of parafunctional facets and anamnesis of parafunctional tooth clenching, bruxism, or unilateral chewing;
• Presence of obvious dentition crowding or spacing, malposed, supernumerary or fractured tooth, visible caries, tooth abrasion/hypersensitivity, toothache, periodontal disease, or occlusal discomfort;
• Fixed or removable restorations, tooth filling, or occlusal adjustment that affected the occlusal surfaces;
• Previous or concurrent orthodontic, orthognathic, or TMJ treatment.

Sponsors & Collaborators

• Stomatological Hospital Affiliated with Fujian Medical University: lead

Study Sites (1)

The Affiliated Stomatological Hospital of Fujian Medical University

Fuzhou, Fujian, 350002, China

Location

Related Publications (1)

• Xiaojie X, Yiling C, Honglei L, Jiamei P, Xiaoyong W, Hao Y, Hui C. Comparative analysis of myoelectric activity and mandibular movement in healthy and nonpainful articular temporomandibular disorder subjects. Clin Oral Investig. 2024 Oct 21;28(11):605. doi: 10.1007/s00784-024-05957-z.

  PMID: 39428401 DERIVED

MeSH Terms

Conditions

Temporomandibular Joint Disorders; Disease

Condition Hierarchy (Ancestors)

Craniomandibular Disorders; Mandibular Diseases; Jaw Diseases; Musculoskeletal Diseases; Joint Diseases; Muscular Diseases; Stomatognathic Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 12, 2024
• First Posted: April 18, 2024
• Study Start: February 1, 2022
• Primary Completion: July 15, 2022
• Study Completion: February 10, 2023
• Last Updated: April 18, 2024

Record last verified: 2024-04

Locations

CN (1)