Procalcitonin as a Marker of Severity of Non-cystic Fibrosis Bronchiectasis in Children

NCT06352944 | Not Yet Recruiting DMC FDA Device

• 1 other identifier: AssiutMD
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to evaluate the role of procalcitonin in bronchoalveolar lavage as a biomarker for assessment of severity of non-CF bronchiectasis in children in correlation with other markers (functional and radiological severity )

Conditions

Non-cystic Fibrosis Bronchiectasis

Outcome Measures

Primary Outcomes (1)

• procalcitonin level in bronchoalveolar lavage as a biomarker for assessment of severity of non-CF bronchiectasis in children

  comparison between procalcitonin level in Bronchoalveolar lavage and other markers of severity of bronchiectasis

  2 years

Interventions

procalcitonin DIAGNOSTIC_TEST

level of procalcitonin in bronchoalveolar lavage

Eligibility Criteria

• Age: 6 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children aged from 6 to 18 years diagnosed with Non-cystic fibrosis bronchiectasis

You may qualify if:

• Children of both sex
• Children aged from 6-17 years old.
• Documented diagnosis of non-CF bronchiectasis by confirmed bronchiectasis findings using high-resolution computed tomographic (HRCT) lung scanning, and clinical symptoms consistent with bronchiectasis with a negative sweat test

You may not qualify if:

• Age less than 6 years or more than 17 years.
• Children Diagnosed with cystic fibrosis bronchiectasis with confirmed positive sweat chloride test(6).
• If there was a history of a recent exacerbation during the previous month preceding the study.

Sponsors & Collaborators

• Assiut University: lead

Study Officials

• Yasser F abdelrahem, professor

  Assiut University

  STUDY DIRECTOR

Central Study Contacts

maram M amir, lecturer

CONTACT

01014808876; maramamir1994@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer

Study Record Dates

• First Submitted: April 3, 2024
• First Posted: April 8, 2024
• Study Start: July 1, 2024
• Primary Completion: July 1, 2025
• Study Completion (Estimated): July 1, 2026
• Last Updated: April 17, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share