NCT06346795

Brief Summary

In the study, Class II restorations will be performed with G-aenial Universal Injectable (GC/ Tokyo, Japan), Grandio Flow (VOCO/ Germany), and Clearfil Majesty Flow (Kuraray/ Japan) composites will evaluated. Restorations will be assessed according to modified USPHS criteria in 1st week, 6th months, and 12th months from the placement date. The Chi-square test will used for statistical analysis of the difference between the groups, and the Cochran Q test will used for the significance of the difference between time-dependent changes within each group (p\<0.05).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2024

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 29, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 4, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

June 1, 2024

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2024

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2025

Completed
Last Updated

April 25, 2024

Status Verified

April 1, 2024

Enrollment Period

6 months

First QC Date

March 29, 2024

Last Update Submit

April 24, 2024

Conditions

Outcome Measures

Primary Outcomes (8)

  • Retention

    No loss of restorative material

    7th day, 6th month, 12th month.

  • Color match

    The restoration matches the adjacent tooth structure in color and translucency

    7th day, 6th month, 12th month.

  • Marginal discoloration

    There is no discoloration anywhere on the margin between the restoration and the tooth structure

    7th day, 6th month, 12th month.

  • Marginal adaptation

    There is no visible evidence of a crevice along the margin into which the explorer will penetrate

    7th day, 6th month, 12th month.

  • Secondary caries

    No evidence of secondary caries

    7th day, 6th month, 12th month.

  • Surface texture

    The surface of the restoration does not have any defects

    7th day, 6th month, 12th month.

  • Anatomical form

    The restoration is continuous with the existing anatomic form

    7th day, 6th month, 12th month.

  • Postoperative sensitivity

    No postoperative sensitivity, after the restorative procedure and during the study

    7th day, 6th month, 12th month.

Study Arms (3)

G-aenial Universal Injectable

EXPERIMENTAL
Other: High-filling flowable dental composite

Grandio Flow

EXPERIMENTAL
Other: High-filling flowable dental composite

Clearfil Majesty Flow

EXPERIMENTAL
Other: High-filling flowable dental composite

Interventions

Class II restorations will be performed with G-aenial Universal Injectable, Grandio Flow, and Clearfil Majesty Flow high-filling flowable composites.

Clearfil Majesty FlowG-aenial Universal InjectableGrandio Flow

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • A patient presenting with;
  • over 18 years of age
  • a normal periodontal status and good general health
  • proximal caries that are similar in size to premolar and molar teeth
  • vital teeth
  • teeth in contact with the opposing tooth and subjected to normal occlusal forces
  • attend follow-up appointments

You may not qualify if:

  • poor oral hygiene status
  • those with severe or chronic periodontitis
  • absence of adjacent and antagonist teeth
  • potential behavioral problems (e.g. bruxism)
  • allergy to any product used in the study
  • exposure of the pulp during cavity preparation
  • systemically unhealthy
  • pregnant and lactating women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Selcuk University, Faculty of Dentistry, Restorative Dentistry Department

Konya, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth DemineralizationTooth DiseasesStomatognathic Diseases

Study Officials

  • Merve Gürses

    Selcuk University, Faculty of Dentistry, Department of Restorative Dentistry

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Proffesor

Study Record Dates

First Submitted

March 29, 2024

First Posted

April 4, 2024

Study Start

June 1, 2024

Primary Completion

December 1, 2024

Study Completion

June 1, 2025

Last Updated

April 25, 2024

Record last verified: 2024-04

Data Sharing

IPD Sharing
Will not share

Locations