NCT06345690

Brief Summary

Registry is to observe and trend patterns of care and outcomes for patients treated with VIA Disc NP.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
8mo left

Started Feb 2024

Typical duration for all trials

Geographic Reach
1 country

26 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress77%
Feb 2024Jan 2027

Study Start

First participant enrolled

February 27, 2024

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

March 6, 2024

Completed
28 days until next milestone

First Posted

Study publicly available on registry

April 3, 2024

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2027

Last Updated

February 6, 2026

Status Verified

February 1, 2026

Enrollment Period

2.8 years

First QC Date

March 6, 2024

Last Update Submit

February 3, 2026

Conditions

Keywords

Back Pain

Outcome Measures

Primary Outcomes (4)

  • Numeric Pain Rating Scale (NPRS)

    Change in Numeric Rating Scale (NRS) scores. Eleven point pain scale used for patient self-reporting of back pain, which ranges from 0 (no pain) to 10 (the worst pain imaginable).

    1, 3, 6, & 12 months

  • Oswestry Disability Index (ODI)

    Change in scores from Oswestry Disability Index (ODI). An index comprising of ten categories of function to quantify disability due to back pain.

    1, 3, 6, & 12 months

  • Patient Satisfaction

    Patient reported assessment of treatment regarding their experience with the procedure. Four different responses, which range from Not at all satisfied (worst) to Extremely Satisfied (best).

    1, 3, 6, & 12 months

  • Frequency of Pain Medication Use

    Assesses the frequency and type of pain medication administered to participants at baseline and follow-up visits scheduled at 1, 3, 6, and 12 months. Data will be collected to track changes in pain medication usage over time.

    1, 3, 6, & 12 months

Study Arms (1)

VIA Disc NP

Patients meeting study criteria receiving Vivex VIA Disc NP injection as treatment

Other: VIA Disc NP

Interventions

VIA Disc NP - Allograft tissue injection

VIA Disc NP

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants diagnosed with and treated for back pain.

You may qualify if:

  • Willing to sign the informed consent and deemed capable of complying with the requirements of the study protocol
  • years of age or older
  • Literate, able to speak and read English, and able to complete questionnaires independently
  • Subject received a VIA Disc NP injection with 1 or more levels within 90 days of the baseline visit.

You may not qualify if:

  • Participant did not receive VIA Disc NP injection
  • Participant is pregnant (self-reported, no special study pregnancy testing needed).
  • Any contraindications as noted in the VIA Disc NP Instructions for Use
  • Previous treatment with VIA Disc NP

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (26)

Mocek Spine

Little Rock, Arkansas, 72205, United States

RECRUITING

MD Pain

Englewood, Colorado, 80112, United States

RECRUITING

Western Rockies Interventional Pain

Grand Junction, Colorado, 81505, United States

RECRUITING

The Denver Spine & Pain Institute

Greenwood Village, Colorado, 80111, United States

WITHDRAWN

Premier Spine and Pain Institute

Thornton, Colorado, 80229, United States

RECRUITING

The Orthopedic Institute

Gainesville, Florida, 32605, United States

RECRUITING

Raso Pain Center

Jupiter, Florida, 33477, United States

RECRUITING

Interventional Spine Care of the Palm Beaches

West Palm Beach, Florida, 33407, United States

RECRUITING

Horizon Clinical Research

Jasper, Georgia, 30143, United States

RECRUITING

The Orthopedic Research Foundation, Inc.

Fishers, Indiana, 46278, United States

RECRUITING

Interventional Pain Specialists - Pain Clinic

Opelousas, Louisiana, 70570, United States

RECRUITING

Paradigm Health System

Slidell, Louisiana, 70461, United States

RECRUITING

Premier Pain Solutions

Asheville, North Carolina, 28803, United States

RECRUITING

Comprehensive Pain Consultants of the Carolinas

Hendersonville, North Carolina, 28791, United States

RECRUITING

Crystal Coast Pain Management

Morehead City, North Carolina, 28557, United States

RECRUITING

Crystal Coast Pain Management

New Bern, North Carolina, 28560, United States

RECRUITING

Align Interventional Pain

Edmond, Oklahoma, 73013, United States

RECRUITING

Fox Chase Pain Management_Delaware Valley Pain and Spine Institute (DVPSI)

Trevose, Pennsylvania, 19053, United States

WITHDRAWN

Atlantic Coast Spine & Pain

Conway, South Carolina, 29526, United States

RECRUITING

Renew Pain Solutions

Greenville, South Carolina, 29607, United States

RECRUITING

Specialists in Pain Managment

Chattanooga, Tennessee, 37404, United States

RECRUITING

Freedom Spine

Boerne, Texas, 78006, United States

TERMINATED

Corpus Chrisi Pain Medicine

Corpus Christi, Texas, 78415, United States

RECRUITING

Advanced Spine and Pain Center

San Antonio, Texas, 78240, United States

RECRUITING

Pain and Wellness Institute of Texas

Spring Branch, Texas, 80700, United States

RECRUITING

Precision Spine Care

Tyler, Texas, 75701, United States

RECRUITING

MeSH Terms

Conditions

Back PainLow Back Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Leslie Zaccari

    Sponsor - Vivex Biologics

    STUDY DIRECTOR

Central Study Contacts

Leslie Zaccari

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 6, 2024

First Posted

April 3, 2024

Study Start

February 27, 2024

Primary Completion (Estimated)

January 1, 2027

Study Completion (Estimated)

January 1, 2027

Last Updated

February 6, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations