NCT06345274

Brief Summary

The goal of this clinical trial is to evaluate the effectiveness and implementation of measurement-based care, which involves the systematic use of client self-report data to inform and enhance treatment, in opioid treatment programs using a pilot hybrid effectiveness-implementation study design. The main questions this study aims to answer are: 1) is measurement based care effective for improving patient treatment attendance and opioid abstinence, and 2) can measurement based care be implemented with fidelity in opioid treatment programs? Participants in this study will be opioid treatment program leaders and treatment providers. Leaders and treatment providers will participate in measurement-based care implementation strategies such as training and consultation to help them use measurement-based care with their patients. There is no comparison group for this study, however researchers will compare effectiveness outcomes prior to and post measurement-based care implementation and will evaluate changes in measurement-based care use with fidelity post implementation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2024

Typical duration for not_applicable

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 21, 2024

Completed
13 days until next milestone

First Posted

Study publicly available on registry

April 3, 2024

Completed
21 days until next milestone

Study Start

First participant enrolled

April 24, 2024

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 14, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 14, 2026

Completed
Last Updated

April 27, 2026

Status Verified

April 1, 2026

Enrollment Period

2 years

First QC Date

March 21, 2024

Last Update Submit

April 22, 2026

Conditions

Keywords

Opioid Use DisorderOpioid Treatment ProgramsMeasurement-Based CareImplementation Science

Outcome Measures

Primary Outcomes (3)

  • Patient treatment attendance (effectiveness outcome)

    Treatment attendance will include both completion of medication for opioid use disorder (MOUD) dosing visits and attendance at treatment sessions. Data to be extracted from opioid treatment program electronic medical records include the number of treatment sessions/visits attended for each patient (e.g., MOUD dosing visits and individual/group counseling appointments) and the total number of treatment visits scheduled for each patient.

    Assessed for 6 months for each patient both pre and post measurement based care implementation. Data will be extracted from the opioid treatment program electronic medical record.

  • Patient treatment attendance (effectiveness outcome)

    Treatment attendance will include both completion of medication for opioid use disorder (MOUD) dosing visits and attendance at treatment sessions. Data to be extracted from opioid treatment program electronic medical records include the the total number of weeks each patient was retained in treatment after an initial intake appointment.

    Assessed for 6 months for each patient both pre and post measurement based care implementation. Data will be extracted from the opioid treatment program electronic medical record.

  • Treatment provider measurement based care exposure (implementation outcome)

    The total number of monthly completed counseling or treatment sessions delivered by treatment providers will be extracted from the opioid treatment program electronic medical record. The research team will compute monthly MBC exposure values by dividing the total number of sessions with MBC administration documentation by the total number of sessions completed for each patient.

    Assessed for 6 months for each patient post measurement based care implementation. Data will be extracted from the opioid treatment program electronic medical record.

Secondary Outcomes (2)

  • Patient opioid abstinence (effectiveness outcome)

    Assessed for 6 months for each patient both pre and post measurement based care implementation. Data will be extracted from the opioid treatment program electronic medical record.

  • Treatment provider measurement based care fidelity (implementation outcome)

    Assessed for 6 months for each patient post measurement based care implementation. Data will be extracted from the opioid treatment program electronic medical record.

Study Arms (1)

Measurement Based Care Implementation

EXPERIMENTAL

All participating opioid treatment programs will receive this arm.

Behavioral: Measurement Based Care Training and Monthly Consultation

Interventions

Participating opioid treatment program leaders and treatment providers will receive two measurement-based care implementation strategies: 1) didactic training including a total of four hours of workshop training led by a measurement-based care expert, and 2) monthly consultation calls led by a measurement-based care expert for 6 months.

Measurement Based Care Implementation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Provide supervision or oversight to treatment providers or provide administrative oversight at the OTP
  • Conduct supervision or oversight primarily in English
  • Are considered a treatment provider at the OTP providing direct patient care
  • Conduct treatment primarily in English

You may not qualify if:

  • Must be a new patient at the opioid treatment program in the 6 months pre or post measurement-based care implementation
  • Younger than 18 years of age
  • Does not have electronic medical records

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Family Guidance Centers, Inc.

Aurora, Illinois, 60505, United States

Location

Northwestern University Feinberg School of Medicine

Chicago, Illinois, 60611, United States

Location

Family Guidance Centers, Inc.

Chicago, Illinois, 60654, United States

Location

Family Guidance Centers, Inc.

Des Plaines, Illinois, 60016, United States

Location

Family Guidance Centers, Inc.

Joliet, Illinois, 60435, United States

Location

Related Publications (1)

  • Scott K, Guigayoma J, Palinkas LA, Beaudoin FL, Clark MA, Becker SJ. The measurement-based care to opioid treatment programs project (MBC2OTP): a study protocol using rapid assessment procedure informed clinical ethnography. Addict Sci Clin Pract. 2022 Aug 19;17(1):44. doi: 10.1186/s13722-022-00327-0.

    PMID: 35986380BACKGROUND

MeSH Terms

Conditions

Opioid-Related Disorders

Condition Hierarchy (Ancestors)

Narcotic-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 21, 2024

First Posted

April 3, 2024

Study Start

April 24, 2024

Primary Completion

April 14, 2026

Study Completion

April 14, 2026

Last Updated

April 27, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

The study protocol and statistical analysis plan for this study was published in 2022 in the Addiction Science and Clinical Practice journal (https://doi.org/10.1186/s13722-022-00327-0). Additional data (analytic code, participant-level data) can be requested from the Principal Investigator. Analysis files will be constructed from the electronic data and will be stripped of identifying information. Specifically, participants will be identified with a numeric identifier that is not related to any element of their personal identifying information. No names, addresses, telephone numbers, email addresses, medical record numbers, etc. will be retained in the de-identified files.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Study Protocol was published in 2022 in the Addiction Science and Clinical Practice Journal. Analytic code and participant-level data will be made ready for distribution within 12 months of study completion.
Access Criteria
Data will only be shared with external investigators when a data use agreement (DUA) is executed between Northwestern University and the requester's institution. The DUA will specify the requested data elements (each of which must be justified), the specific research question, the timeline for the project, and schedule for data destruction.

Locations