Compliance With ERAS and Five Year Survival After Colorectal Cancer Treatment

NCT06342687 | Completed

• 1 other identifier: JagiellonianU 1
• Study Type: observational
• Target: 468
• Locations: 1 country
• Sites: 1

Brief Summary

The Enhanced Recovery after Surgery (ERAS) protocol has transformed perioperative care, representing a significant paradigm shift in managing colorectal cancer patients. While the immediate benefits of Enhanced Recovery After Surgery (ERAS) in expediting postoperative recovery are well-documented and widely acknowledged, it is essential to investigate its long-term implications, particularly its influence on survival rates. The aim of this study will be to analyse the impact of compliance with the ERAS protocol on long- term outcomes after laparoscopic colorectal resection.

Conditions

Colorectal Cancer; ERAS

Outcome Measures

Primary Outcomes (1)

• Post operative 5 year survival rate

  5 years

Study Arms (2)

Group 1

with a compliance rate with ERAS below 80%

Group 2

with a compliance rate with ERAS of 80% or above

Procedure: High compliance with ERAS protocol

Interventions

High compliance with ERAS protocol PROCEDURE

Patients were categorized into two groups based on their adherence to the ERAS protocol: group 1 with a compliance rate below 80% and group 2 with a compliance rate of 80% or above.

Group 2

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The patients will be divided into two groups based on ERAS protocol compliance. Group 1 comprised patients with adherence below 80%, while Group 2 consisted of individuals who maintained adherence levels of no less than 80%. We established this threshold based on the compliance target set in our clinic.

You may qualify if:

• patients undergoing treatment for colorectal cancer

You may not qualify if:

• primary open or emergency surgery,
• transanal endoscopic microsurgery (TEM),
• stage IV of the disease according to the American Joint Committee on Cancer (AJCC) classification,
• multivisceral resection,
• concomitant inflammatory bowel diseases,
• intensive care unit stay immediately after surgery
• lost-to-follow-up patients.

Sponsors & Collaborators

• Jagiellonian University: lead

Study Sites (1)

Jagiellonian University Medical College

Krakow, Lesser Poland Voivodeship, 31-008, Poland

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD PhD

Study Record Dates

• First Submitted: March 26, 2024
• First Posted: April 2, 2024
• Study Start: January 1, 2018
• Primary Completion: December 31, 2022
• Study Completion: December 31, 2023
• Last Updated: April 2, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)