NCT06340464

Brief Summary

This prospective study investigate prognostic values and compare the role of nutritional status by using GNRI, MNA, and PNI in predicting post-operative pulmonary complication among elderly patients with cardiac surgery.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
229

participants targeted

Target at P75+ for all trials

Timeline
7mo left

Started Mar 2024

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress79%
Mar 2024Nov 2026

Study Start

First participant enrolled

March 21, 2024

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

March 25, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 1, 2024

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2025

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2026

Expected
Last Updated

April 1, 2024

Status Verified

March 1, 2024

Enrollment Period

1.8 years

First QC Date

March 25, 2024

Last Update Submit

March 25, 2024

Conditions

Cardiac SurgeryElderly PatientPostoperative Pulmonary ComplicationNutrition Scoring System

Keywords

Cardiac surgeryElderly, AgedPostoperative pulmonary complicationNutrition scoring systemGNRIMNAPNI

Outcome Measures

Primary Outcomes (1)

  • Postoperative pulmonary complication

    PPCs such as pneumonia, pulmonary embolism, ventilation longer than 24 h, pleural effusions necessitating drainage and reintubation within 72 h of extubation

    1 month

Interventions

GNRI, PNI, MNAOTHER

Nutrition scoring systems

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Elderly patients (aged ≥ 60 years old) who undergoing cardiac surgery in Songklanagarind hospital, Songkla, Thailand

You may qualify if:

  • Elderly patient age ≥ 60 years
  • Open heart surgical procedure on pump (CABG, valvular disease, combine CABG and valve surgery
  • Elective surgery

You may not qualify if:

  • \- Emergency surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University

Hat Yai, Changwat Songkhla, 90110, Thailand

RECRUITING

MeSH Terms

Interventions

Serpin E2

Intervention Hierarchy (Ancestors)

Protease NexinsProteinase Inhibitory Proteins, SecretoryPeptidesAmino Acids, Peptides, and ProteinsPlasminogen InactivatorsSerpinsProteins

Study Officials

  • Panalee Kittisopaporn

    Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Panalee Kittisopaporn

CONTACT

66832422540kit.panalee@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Month
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Miss

Study Record Dates

First Submitted

March 25, 2024

First Posted

April 1, 2024

Study Start

March 21, 2024

Primary Completion

December 31, 2025

Study Completion (Estimated)

November 30, 2026

Last Updated

April 1, 2024

Record last verified: 2024-03

Locations

TH(1)