Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teeth and Premolars in Symptomatic Irreversible Pulpitis

NCT06333730 | Recruiting

• 1 other identifier: PMC
• Study Type: interventional
• Target: 96
• Locations: 1 country
• Sites: 1

Brief Summary

Symptomatic irreversible pulpitis is a painful condition that requires anesthesia to perform effective dental procedures. The mental nerve block and inferior alveolar nerve block are two commonly used techniques for achieving anesthesia in the mandibular teeth. Study design: This randomized clinical trial study Number of participants: 96 participants which will be randomly divided into two groups: MINB and IANB. Inclusion criteria: Participants with mandibular premolars or lower anterior experiencing sharp and persistent pain in response to thermal stimuli and an electric pulp tester, as well as bleeding during access opening, will be included. Exclusion criteria: Participants with a medical history, allergies or contraindications to the local anesthetic, pregnant or breastfeeding women, those taking pain-affecting medication, or those experiencing pain in more than one tooth will be excluded. Both techniques will use 2% lidocaine and adrenaline 1:80,000. Age, gender, and the efficacy of anesthesia will be recorded in both groups. The chi-square test will be used for comparison.

Conditions

Symptomatic Irreversible Pulpitis

Outcome Measures

Primary Outcomes (1)

• COMPARISON OF ANESTHETIC EFFICACY OF MENTAL NERVE BLOCK VERSUS INFERIOR ALVEOLAR NERVE BLOCK IN MANDIBULAR ANTERIORS TEETH AND PREMOLARS IN SYMPTOMATIC IRREVERSIBLE PULPITIS

  Pain after anesthesia in both groups will be assessed through Visual Pain analogue scale and greater than 3 will be considered ineffective

  Two months

Study Arms (2)

Inferior Alveolar Nerve Block (IANB)

EXPERIMENTAL

48 patients will be randomly selected in inferior alveolar nerve block group

Procedure: inferior alveolar nerve block

Mental Nerve Block (MNB)

EXPERIMENTAL

48 patients will be randomly selected in mental nerve block group

Procedure: mental nerve block

Interventions

inferior alveolar nerve block PROCEDURE

After informed consent, the needle will be inserted into the muco-buccal fold adjacent to the mandibular molars and advanced it towards the mandibular foramen, aiming slightly anteriorly and superiorly. Aspirating to check for blood or resistance, the needle will be repositioned if either was present. Once the needle will be correctly positioned, the dental practitioner will slowly inject 1.8-1.9 mL of the anesthetic solution.

Inferior Alveolar Nerve Block (IANB)

mental nerve block PROCEDURE

After informed consent, the needle will be inserted into the buccal fold between the lower premolars. Aspirating to check for blood or resistance. Once needle is correctly positioned, 0.6-0.9 ml of the anesthetic solution will be deposited.

Mental Nerve Block (MNB)

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Participants with mandibular premolars or lower anterior
• Experiencing sharp and persistent pain in response to thermal stimuli and an electric pulp tester
• Bleeding during access opening

You may not qualify if:

• Participants with a medical history
• Allergies or contraindications to the local anesthetic
• Pregnant or breastfeeding women
• Patient taking pain-affecting medication
• Patient experiencing pain in more than one tooth

Sponsors & Collaborators

• Prime Foundation: lead

Study Sites (1)

Peshawar Dental College

Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan

RECRUITING

Study Officials

• Saifa Rashad, BDS

  Peshawar Dental College

  STUDY CHAIR

Central Study Contacts

Iftikhar Akbar, FCPS, CHIPE

CONTACT

00923479368676; driftikhar156@hotmail.com

Marghalara Noor, BDS

CONTACT

00923359631393; marghalaranoor96@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Operative dentistry & Endodontic, Professor, Principal investigator

Study Record Dates

• First Submitted: October 31, 2023
• First Posted: March 27, 2024
• Study Start: April 1, 2024
• Primary Completion: May 30, 2024
• Study Completion: June 20, 2024
• Last Updated: March 27, 2024

Record last verified: 2024-03

Locations

PA (1)