NCT06331754

Brief Summary

The primary objective of this study is to reliably estimate the difference in blood pressure control of a technology-enabled solution for blood pressure (BP) management over usual care. The study will also assess patient and provider satisfaction with the solution. Finally, the investigators will estimate the economic impact of the intervention in terms of resource utilization.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,500

participants targeted

Target at P75+ for not_applicable hypertension

Timeline
Completed

Started Mar 2024

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 18, 2024

Completed
Same day until next milestone

Study Start

First participant enrolled

March 18, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 26, 2024

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 17, 2025

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 17, 2026

Completed
Last Updated

March 26, 2024

Status Verified

March 1, 2024

Enrollment Period

1.5 years

First QC Date

March 18, 2024

Last Update Submit

March 22, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Difference in SBP change

    Difference in mean change in systolic blood pressure (SBP)

    6 months after enrollment

Secondary Outcomes (2)

  • HEDIS proportion

    6 months after enrollment

  • Difference in DBP change

    6 months after enrollment

Other Outcomes (7)

  • Home measured change in SBP and DBP

    6 months

  • Patient satisfaction

    6 months

  • Provider satisfaction

    6 months

  • +4 more other outcomes

Study Arms (2)

Technology-enabled blood pressure management

EXPERIMENTAL

The intervention will consist of a technology-enabled remote hypertension management program. Participants will be given a cellular blood pressure (BP) cuff and patients with heart failure and chronic kidney disease stage 3b-5 will be given a scale also. Patients will undergo a series of protocolized software-driven medication initiation and titration steps until they reach a blood pressure target of systolic blood pressure \< 130 mmHg and diastolic blood pressure \< 80 mmHg. Patients will be subsequently monitored for up to 12 more months. If their blood pressure increases, they can re-enter active management.

Other: Technology-enabled blood pressure management

No intervention

NO INTERVENTION

Patients meeting inclusion care undergoing usual care in control clinics.

Interventions

The intervention will consist of a technology-enabled remote hypertension management program.

Technology-enabled blood pressure management

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years - 100 years
  • uncontrolled hypertension: as defined as SBP \> 140 or DBP \> 90 on 2 successive clinic visits

You may not qualify if:

  • hearing impaired
  • visually impaired
  • cognitively impaired
  • hospice care
  • on hemodialysis at enrollment
  • New York Heart Association Class IV heart failure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Central Study Contacts

Rahul C Deo, MD PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: non-blinded pragmatic cluster-randomized controlled trial with a single intervention
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 18, 2024

First Posted

March 26, 2024

Study Start

March 18, 2024

Primary Completion

September 17, 2025

Study Completion

March 17, 2026

Last Updated

March 26, 2024

Record last verified: 2024-03