NCT06331221

Brief Summary

The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Nov 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 2, 2023

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

March 19, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 26, 2024

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 5, 2024

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 15, 2024

Completed
Last Updated

July 11, 2024

Status Verified

March 1, 2024

Enrollment Period

6 months

First QC Date

March 19, 2024

Last Update Submit

July 9, 2024

Conditions

Keywords

Muscle FatigueKneeJoint Position SenseProprioception

Outcome Measures

Primary Outcomes (3)

  • Absolute angular error

    The absolute value of the difference between the target range and the achieved range

    Change from Baseline (Before) to Immediately after interventions or control (After)

  • Relative angular error

    The arithmetic difference between the target range and the range achieved

    Change from Baseline (Before) to Immediately after interventions or control (After)

  • Variable angular error

    The standard deviation of the 3 repositionings

    Change from Baseline (Before) to Immediately after interventions or control (After)

Study Arms (5)

Control Condition

NO INTERVENTION

5-minute rest period.

Quadriceps_Concentric

ACTIVE COMPARATOR

40 consecutive maximal concentric contractions of quadriceps at 30º/s

Other: Muscle fatigue Protocol

Quadriceps_Eccentric

ACTIVE COMPARATOR

40 consecutive maximal eccentric contractions of quadriceps at 30°/s

Other: Muscle fatigue Protocol

Hamstrings_Concentric

ACTIVE COMPARATOR

30 consecutive maximal concentric contractions of hamstrings at 30º/s

Other: Muscle fatigue Protocol

Hamstrings_Eccentric

ACTIVE COMPARATOR

30 consecutive maximal eccentric contractions of the hamstrings at 30º/s

Other: Muscle fatigue Protocol

Interventions

Four experimental conditions consisting of different local muscle fatigue protocols performed in the isokinetic dynamometer in random order, with at least one week of interval between them.

Hamstrings_ConcentricHamstrings_EccentricQuadriceps_ConcentricQuadriceps_Eccentric

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • males aged between 18 and 30 years;
  • without current or previous knee pathology or surgery;
  • with a low or moderate physical activity level, according to the International Physical Activity Questionnaire;
  • normal Body Mass Index (under 24.9 kg/m2), according to the World Health Organization.

You may not qualify if:

  • those with cardiorespiratory, neurological or vestibular pathologies;
  • with positive knee integrity tests (anterior drawer, Lachman's test, posterior drawer; valgus and varus stress testes); and
  • those taking any medication that can affect motor control (sedatives, anxiolytics, antibiotics, analgesics, NSAIDs or myorelaxants).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculdade de Desporto, Universidade do Porto

Porto, 4200, Portugal

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 19, 2024

First Posted

March 26, 2024

Study Start

November 2, 2023

Primary Completion

May 5, 2024

Study Completion

May 15, 2024

Last Updated

July 11, 2024

Record last verified: 2024-03

Locations