NCT06330558

Brief Summary

Context: Adrenalectomy for pheochromocytoma (PHEO) poses difficulties due to the elevated chance of conversion. The objective of this study was to conduct a comparative analysis of the occurrence and determinants of conversion in left-sided abdominal laparoscopic adrenalectomy (LLA) and right-sided abdominal laparoscopic adrenalectomy (RLA). Methods: A retrospective analysis was conducted to include a total of 271 patients diagnosed with PHEO. These patients were separated into two groups: LRA (N=121) and LLA (N=150). The study period spanned from September 2016 to September 2023.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
271

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2016

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2016

Completed
7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2023

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

March 19, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 26, 2024

Completed
Last Updated

March 28, 2024

Status Verified

March 1, 2024

Enrollment Period

7 years

First QC Date

March 19, 2024

Last Update Submit

March 26, 2024

Conditions

Adrenal Tumor

Outcome Measures

Primary Outcomes (1)

  • conversion

    number of conversion

    intraoperative

Study Arms (2)

group A

laparoscopic right adrenalectomy

Procedure: laparoscopic right adrenalectomy

Group B

laparoscopic left adrenalectomy

Procedure: laparoscopic right adrenalectomy

Interventions

laparoscopic right adrenalectomyPROCEDURE

adrenalectomy

Group Bgroup A

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

An analysis of individuals who have undergone TLA and have unilateral PHEO of any size, aged over 18 years, and of both sexes.

You may qualify if:

  • Unilateral pheochromocytoma of any size, over 18 years old, both males and females

You may not qualify if:

  • Patients undergoing initial open adrenalectomy, - Additional surgical interventions during total laparoscopic adrenalectomy, - Partial adrenalectomy,
  • Bilateral PHEOS. Hemorrhagic diathesis, Structural deformity Pregnancy,
  • \- Prior unilateral abdominal surgery, data is absent. The preoperative diagnosis is ambiguous. Hereditary (PHEO), or recurrent PHEO

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Adrenal Gland Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsAdrenal Gland DiseasesEndocrine System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professour of general and laparoscopic surgery

Study Record Dates

First Submitted

March 19, 2024

First Posted

March 26, 2024

Study Start

September 1, 2016

Primary Completion

September 1, 2023

Study Completion

September 1, 2023

Last Updated

March 28, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will not share