Assessment System of Sarcopenia in Lung Cancer Patients

NCT06327594 | Recruiting

• 1 other identifier: XTang-0002
• Study Type: observational
• Target: 1,500
• Locations: 1 country
• Sites: 1

Brief Summary

1. 1.To explore the diagnostic value of musculoskeletal cross-modal imaging assessment system of ultrasound combined with abdominal CT/MRI for sarcopenia in patients with lung cancer.
2. 2.To explore the value of musculoskeletal cross-modal imaging assessment system of ultrasound combined with abdominal CT/MRI in evaluating the prognosis and the effect of nutritional support in patients with lung cancer during perioperative period.
3. 3.To explore the value of musculoskeletal cross-modal imaging assessment system of ultrasound combined with abdominal CT/MRI in evaluating the long-term prognosis of patients with lung cancer.

Conditions

Sarcopenia; Lung Cancer; Ultrasound

Outcome Measures

Primary Outcomes (2)

• Death

  Within 2 years after the initial ultrasound examination

• Perioperative complications

  Including local incision complications (infection, dehiscence); atelectasis/pulmonary infection; urinary tract infections; postoperative bleeding; deep venous thrombosis of the lower extremity; urinary retention; sepsis; hypoproteinemia, etc.

  Within 7 days after the surgery.

Study Arms (2)

Lung cancer patients with sarcopenia

Diagnostic Test: ultrasound scan; Diagnostic Test: CT/MRI scan

Lung cancer patients without sarcopenia

Diagnostic Test: ultrasound scan; Diagnostic Test: CT/MRI scan

Interventions

ultrasound scan DIAGNOSTIC_TEST

The patients with lung cancer who are scheduled to undergo radical resection of lung cancer are examined by ultrasound at multiple sites of the whole body, including muscle and fat.

Lung cancer patients with sarcopenia; Lung cancer patients without sarcopenia

CT/MRI scan DIAGNOSTIC_TEST

The patients with lung cancer who are scheduled to undergo radical resection of lung cancer are examined by abdominal CT/MRI.

Lung cancer patients with sarcopenia; Lung cancer patients without sarcopenia

Eligibility Criteria

• Age: 40 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Hospitalized patients scheduled for radical resection of lung cancer.

You may qualify if:

• Hospitalized patients scheduled for radical resection of lung cancer.
• With a CT/MRI examination within 1 week.
• The compliance of examination was good.

You may not qualify if:

• Amputated arm or leg.
• Severe oedema (oedema higher than knee level).
• Implantable pacemaker.
• Impaired consciousness, poor general health, or other reasons that would prevent the individual from completing the study.

Sponsors & Collaborators

• West China Hospital: lead

Study Sites (1)

Xinyi Tang

Chengdu, Sichuan, China

RECRUITING

MeSH Terms

Conditions

Sarcopenia; Lung Neoplasms

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Xinyi Tang

  Department of Medical Ultrasound, West China Hospital, Sichuan University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Xinyi Tang, Dr.

CONTACT

+8615680819215; tangxinyi1996@outlook.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 18, 2024
• First Posted: March 25, 2024
• Study Start: November 1, 2023
• Primary Completion (Estimated): November 1, 2027
• Study Completion (Estimated): November 1, 2028
• Last Updated: March 25, 2024

Record last verified: 2024-03

Locations

CN (1)