NCT06326788

Brief Summary

To determine the effects of Short duration moderate intensity soleus push- ups VS Sustained Soleus Push-ups on lipid profile among Young Population.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
33

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2023

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

March 4, 2024

Completed
18 days until next milestone

First Posted

Study publicly available on registry

March 22, 2024

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 28, 2024

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2024

Completed
Last Updated

May 21, 2024

Status Verified

May 1, 2024

Enrollment Period

10 months

First QC Date

March 4, 2024

Last Update Submit

May 19, 2024

Conditions

Health Behavior

Keywords

lipid profileYoung PopulationPush-upsSoleusSustained

Outcome Measures

Primary Outcomes (1)

  • Change in Lipid Profile

    The primary outcome measure will be the change in lipid profile parameters, including total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides, measured before and after the intervention period. This will provide insight into the direct impact of short duration moderate intensity Soleus push-ups vs sustained Soleus push-ups on lipid metabolism among young individuals.

    baseline to 6 hours

Other Outcomes (1)

  • Adherence to Exercise Protocol

    baseline to 6 hours

Study Arms (2)

Short Duration Moderate Intensity Soleus Push-ups (Group A)

EXPERIMENTAL

Moderate physical activity involving weighted soleus push-ups performed till patient MHR is achieved.

Behavioral: Short Duration Moderate Intensity Soleus Push-ups

Sustained Soleus Push-ups (Group B)

EXPERIMENTAL

sustained soleus push-ups will be performed for up to 270 min.

Behavioral: SUSTAINED SOLEUS PUSH-UPS

Interventions

Short Duration Moderate Intensity Soleus Push-upsBEHAVIORAL

Participants will start soleus pushups in sitting positions. To do so, the participants will be in a seated position, the legs will be at 90 degrees to the floor, and the feet will be placed flat on the ground. Participants will then move their heels up and down continuously. Soleus push-ups will be performed with moderate intensity using weights which will be placed on their laps. Participants will perform this activity till 60-70% of their maximum heart rate is achieved and maintained.

Also known as: Group A
Short Duration Moderate Intensity Soleus Push-ups (Group A)
SUSTAINED SOLEUS PUSH-UPSBEHAVIORAL

Participants will start soles push-ups in sitting. To do so, the participants will be in a seated position, the legs will be at 90 degrees to the floor, and the feet will be placed flat on the ground. Participants will then move their heels up and down continuously. Sustained soleus push-ups will be performed with light intensity for up to 270 mins. No external resistance will be added. Participants will be provided with a maximum 4-minute break time after every 90 mins intervention. In the meantime, their blood sample will be collected.

Also known as: Group B
Sustained Soleus Push-ups (Group B)

Eligibility Criteria

Age18 Years - 26 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Adults (age range: 18-26 )
  • BMI: Healthy Young Adults.
  • Equal number of gender
  • Healthy young Adults.

You may not qualify if:

  • History of metabolic diseases.
  • History of recent fractures.
  • Patient with any lower limb injuries.
  • Knee injuries. The patient is already involved in regular physical exercise and a prescribed diet.
  • Any deformity from childhood
  • DVT and lower limb amputation.
  • Known case of hyperlipidemia.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Riphah Rehabilitation Center

Islamabad, 46600, Pakistan

RECRUITING

Related Publications (5)

  • Durstine JL, Grandjean PW, Cox CA, Thompson PD. Lipids, lipoproteins, and exercise. J Cardiopulm Rehabil. 2002 Nov-Dec;22(6):385-98. doi: 10.1097/00008483-200211000-00002.

    PMID: 12464825BACKGROUND

  • Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Shay CM, Spartano NL, Stokes A, Tirschwell DL, VanWagner LB, Tsao CW; American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association. Circulation. 2020 Mar 3;141(9):e139-e596. doi: 10.1161/CIR.0000000000000757. Epub 2020 Jan 29.

    PMID: 31992061BACKGROUND

  • Holten MK, Zacho M, Gaster M, Juel C, Wojtaszewski JF, Dela F. Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes. 2004 Feb;53(2):294-305. doi: 10.2337/diabetes.53.2.294.

    PMID: 14747278BACKGROUND

  • Swain DP, Franklin BA. Comparison of cardioprotective benefits of vigorous versus moderate intensity aerobic exercise. Am J Cardiol. 2006 Jan 1;97(1):141-7. doi: 10.1016/j.amjcard.2005.07.130. Epub 2005 Nov 16.

    PMID: 16377300BACKGROUND

  • Taube W, Kullmann N, Leukel C, Kurz O, Amtage F, Gollhofer A. Differential reflex adaptations following sensorimotor and strength training in young elite athletes. Int J Sports Med. 2007 Dec;28(12):999-1005. doi: 10.1055/s-2007-964996. Epub 2007 May 11.

    PMID: 17497570BACKGROUND

MeSH Terms

Conditions

Health Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Waqar Ahmed Awan, PhD

    Riphah International University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mehnoor Butt

CONTACT

335 5400831mehnoorarshad1109@gmail.com

Waqar Ahmed Awan, PhD

CONTACT

333 5348846waqar.ahmed@riphah.edu.pk

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 4, 2024

First Posted

March 22, 2024

Study Start

October 1, 2023

Primary Completion

July 28, 2024

Study Completion

July 30, 2024

Last Updated

May 21, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)