NCT06324955

Brief Summary

The aim of this study is to compare the impact of common (standard of care) language vs positive language used by clinicians during inhalational induction of anesthesia on anxiety and negative behaviors in children. This is a prospective randomized parallel group trial. Patients will be randomized 1:1 to the common/standard language group or the positive language group.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
128

participants targeted

Target at P50-P75 for not_applicable

Timeline
11mo left

Started Apr 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress70%
Apr 2024Apr 2027

First Submitted

Initial submission to the registry

March 8, 2024

Completed
14 days until next milestone

First Posted

Study publicly available on registry

March 22, 2024

Completed
17 days until next milestone

Study Start

First participant enrolled

April 8, 2024

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2027

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2027

Last Updated

January 9, 2026

Status Verified

December 1, 2025

Enrollment Period

2.9 years

First QC Date

March 8, 2024

Last Update Submit

January 8, 2026

Conditions

Keywords

Anesthesia induction

Outcome Measures

Primary Outcomes (1)

  • Induction compliance

    Compliance of children during mask induction as measured by the Induction Compliance Checklist (ICC) from the time patient enters the operating room until loss of lid reflex

    Through Study Completion about 1 day

Secondary Outcomes (2)

  • Length of induction

    Through Study Completion about 1 day

  • Verbal refusal of mask

    Through Study Completion about 1 day

Study Arms (2)

Common/Standard Language Group

ACTIVE COMPARATOR
Behavioral: Standard/common language during induction

Positive Language Group

EXPERIMENTAL
Behavioral: Positive language during induction

Interventions

The anesthesiologist taking care of the patient will use scripted common/standard language during the induction.

Common/Standard Language Group

The anesthesiologist taking care of the patient will use scripted positive language during the induction.

Positive Language Group

Eligibility Criteria

Age5 Years - 10 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • ASA 1 and 2 (Healthy Patients)
  • Non-emergent cases
  • year olds
  • Patients receiving inhalational induction

You may not qualify if:

  • Non-English speaking
  • History of prior inhalational inductions
  • Hearing difficulty
  • Behavioral difficulty (Autism, Oppositional Defiant Disorder)
  • Patients receiving premedication other than midazolam

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Boston Children's Hospital

Boston, Massachusetts, 02115, United States

RECRUITING

MeSH Terms

Conditions

Emergence Delirium

Condition Hierarchy (Ancestors)

DeliriumConfusionNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesPostoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsSigns and SymptomsNeurocognitive DisordersMental Disorders

Study Officials

  • John Fiadjoe, MD

    Boston Children's Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Anesthesiologist

Study Record Dates

First Submitted

March 8, 2024

First Posted

March 22, 2024

Study Start

April 8, 2024

Primary Completion (Estimated)

March 1, 2027

Study Completion (Estimated)

April 1, 2027

Last Updated

January 9, 2026

Record last verified: 2025-12

Locations