NCT06322823

Brief Summary

There are more than million frozen embryo transfers around the world each year; a faster, safer, and cheaper method can save a significant amount of money for patients undergoing IVF treatment worldwide.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
116

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2020

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 13, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 21, 2024

Completed
Last Updated

March 21, 2024

Status Verified

March 1, 2024

Enrollment Period

3 years

First QC Date

March 13, 2024

Last Update Submit

March 19, 2024

Conditions

IVF

Outcome Measures

Primary Outcomes (1)

  • blastocysts survival rate

    The overall survival rate for thawed blastocysts using different thawing method will be compared.

    up to 6 months

Secondary Outcomes (3)

  • ferilization rate

    up to 12 months

  • pregnancy rate

    up to 12 months

  • live birth rate

    up to 24 months

Study Arms (2)

direct thawing

EXPERIMENTAL
Procedure: direct thawing

commercially available vitrification thawing

ACTIVE COMPARATOR
Procedure: Vitrification

Interventions

direct thawingPROCEDURE

Vitrified blastocysts will be thawed directly into 1ml G-TL medium

direct thawing
VitrificationPROCEDURE

Vitrified blastocysts will be thawed using commercially available one-step media.

commercially available vitrification thawing

Eligibility Criteria

Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who are willing to use direct-thawed blastocysts

You may not qualify if:

  • Patients who are not willing to use direct-thawed blastocysts

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

David Yiu Leung Chan

Hong Kong, 000000, Hong Kong

Location

MeSH Terms

Interventions

Vitrification

Intervention Hierarchy (Ancestors)

Phase TransitionPhysical Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 13, 2024

First Posted

March 21, 2024

Study Start

January 1, 2020

Primary Completion

December 31, 2022

Study Completion

December 31, 2023

Last Updated

March 21, 2024

Record last verified: 2024-03

Locations

HK(1)